AIMS: To assess the potential of essential oils and structurally related synthetic food additives in inhibiting the growth of Clostridium perfringens for the control of necrotic enteritis in chickens. METHODS AND RESULTS: The antimicrobial activity of essential oils/compounds was measured by determining the inhibition of bacterial growth. Thirty-three of 66 oils/compounds exhibited > or =80% inhibition. Seven with the highest potency were further studied. The oils/compounds had MIC(95) values between 167 and 425 microg ml(-1). Most of them were tolerant to low pH (2.0) and exhibited minor or no inhibition of Lactobacillus isolates from the chicken intestine. When mixed with chicken ileal digesta, the oils/compounds retained their efficacy against C. perfringens, but had little effect on the total number of lactobacilli and anaerobic bacteria in the digesta. CONCLUSIONS: Some essential oils/compounds demonstrated good potential in controlling C. perfringens. SIGNIFICANCE AND IMPACT OF THE STUDY: This study has identified candidates of essential oils/compounds for in vivo studies for the control of necrotic enteritis in chickens.
AIMS: To assess the potential of essential oils and structurally related synthetic food additives in inhibiting the growth of Clostridium perfringens for the control of necrotic enteritis in chickens. METHODS AND RESULTS: The antimicrobial activity of essential oils/compounds was measured by determining the inhibition of bacterial growth. Thirty-three of 66 oils/compounds exhibited > or =80% inhibition. Seven with the highest potency were further studied. The oils/compounds had MIC(95) values between 167 and 425 microg ml(-1). Most of them were tolerant to low pH (2.0) and exhibited minor or no inhibition of Lactobacillus isolates from the chicken intestine. When mixed with chicken ileal digesta, the oils/compounds retained their efficacy against C. perfringens, but had little effect on the total number of lactobacilli and anaerobic bacteria in the digesta. CONCLUSIONS: Some essential oils/compounds demonstrated good potential in controlling C. perfringens. SIGNIFICANCE AND IMPACT OF THE STUDY: This study has identified candidates of essential oils/compounds for in vivo studies for the control of necrotic enteritis in chickens.
Authors: J M Diaz Carrasco; L M Redondo; E A Redondo; J E Dominguez; A P Chacana; M E Fernandez Miyakawa Journal: Biomed Res Int Date: 2016-09-25 Impact factor: 3.411
Authors: Silje Granstad; Anja B Kristoffersen; Sylvie L Benestad; Siri K Sjurseth; Bruce David; Line Sørensen; Arnulf Fjermedal; Dag H Edvardsen; Gorm Sanson; Atle Løvland; Magne Kaldhusdal Journal: Animals (Basel) Date: 2020-02-03 Impact factor: 2.752
Authors: D Morshedi; T Salmani Kesejini; F Aliakbari; R Karami-Osboo; M Shakibaei; A Tayaranian Marvian; M Khalifeh; M Soroosh Journal: Res Pharm Sci Date: 2014 Nov-Dec