Literature DB >> 19053503

Parallel synthesis of trisubstituted formamidines: a facile and versatile procedure.

Andrea Porcheddu1, Giampaolo Giacomelli, Ivana Piredda.   

Abstract

A focused library of formamidines having several diversity points has been prepared. The use of isocyanate resin as scavenger may offer several practical advantages over conventional procedures, such as the ease of workup and availability. The technique described herein was performed in a parallel synthesis format. The whole protocol has potential use in high throughput synthesis for the preparation and purification of libraries of unsymmetrical formamidines containing sets of different aliphatic substituents.

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Year:  2009        PMID: 19053503     DOI: 10.1021/cc8001124

Source DB:  PubMed          Journal:  J Comb Chem        ISSN: 1520-4766


  2 in total

Review 1.  Comprehensive survey of chemical libraries for drug discovery and chemical biology: 2009.

Authors:  Roland E Dolle; Bertrand Le Bourdonnec; Karin Worm; Guillermo A Morales; Craig J Thomas; Wei Zhang
Journal:  J Comb Chem       Date:  2010-10-05

2.  The synthesis and characterization of Fe2O3@SiO2-SO3H nanofibers as a novel magnetic core-shell catalyst for formamidine and formamide synthesis.

Authors:  Hakimeh Ziyadi; Mitra Baghali; Akbar Heydari
Journal:  Heliyon       Date:  2021-05-29
  2 in total

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