Literature DB >> 1905006

The murine rac1 gene: cDNA cloning, tissue distribution and regulated expression of rac1 mRNA by disassembly of actin microfilaments.

J Moll1, G Sansig, E Fattori, H van der Putten.   

Abstract

A 886 bp cDNA encoding the murine rac1 protein has been isolated. The abundance of rac1 mRNA was determined in fourteen tissues from both mouse and pig. The mRNA 5' non-coding sequence is very rich in G + C, and has the potential to form several stable secondary structures. In addition, this region contains a putative open reading frame of 57 amino acids. Disruption of the actin microfilament network by cytochalasin B in LLC-PK1 cells results in down regulation of rac1 mRNA. In agreement with the proposed role of rac1 in exocytosis, these results could explain the inhibitory effect of cytochalasin B on secretory processes.

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Year:  1991        PMID： 1905006

Source DB:  PubMed          Journal:  Oncogene        ISSN： 0950-9232            Impact factor:   9.867


  26 in total

1.  In vivo observations of myosin II dynamics support a role in rear retraction.

Authors:  P A Clow; J G McNally
Journal:  Mol Biol Cell       Date:  1999-05       Impact factor: 4.138

2.  On how Rac controls hematopoietic stem cell activity.

Authors:  J A Cancelas
Journal:  Transfusion       Date:  2011-11       Impact factor: 3.157

3.  Rac GTPases regulate the morphology and deformability of the erythrocyte cytoskeleton.

Authors:  Theodosia A Kalfa; Suvarnamala Pushkaran; Narla Mohandas; John H Hartwig; Velia M Fowler; James F Johnson; Clinton H Joiner; David A Williams; Yi Zheng
Journal:  Blood       Date:  2006-08-01       Impact factor: 22.113

4.  The monomeric G-proteins Rac1 and/or Cdc42 are required for the inhibition of voltage-dependent calcium current by bradykinin.

Authors:  M A Wilk-Blaszczak; W D Singer; T Quill; B Miller; J A Frost; P C Sternweis; F Belardetti
Journal:  J Neurosci       Date:  1997-06-01       Impact factor: 6.167

Review 5.  Rho GTPases control specific cytoskeleton-dependent functions of hematopoietic stem cells.

Authors:  Ramesh C Nayak; Kyung-Hee Chang; Nataraja-Sarma Vaitinadin; Jose A Cancelas
Journal:  Immunol Rev       Date:  2013-11       Impact factor: 12.988

6.  Rac GTPases in erythroid biology.

Authors:  D G Konstantinidis; A George; T A Kalfa
Journal:  Transfus Clin Biol       Date:  2010-07-23       Impact factor: 1.406

7.  Rac1 promotes intestinal epithelial restitution by increasing Ca2+ influx through interaction with phospholipase C-(gamma)1 after wounding.

Authors:  Jaladanki N Rao; Stephen V Liu; Tongtong Zou; Lan Liu; Lan Xiao; Xian Zhang; Emily Bellavance; Jason X-J Yuan; Jian-Ying Wang
Journal:  Am J Physiol Cell Physiol       Date:  2008-10-15       Impact factor: 4.249

8.  Rac GTPase isoforms Rac1 and Rac2 play a redundant and crucial role in T-cell development.

Authors:  Fukun Guo; Jose A Cancelas; David Hildeman; David A Williams; Yi Zheng
Journal:  Blood       Date:  2008-06-25       Impact factor: 22.113

9.  Cloning and characterization of a tomato GTPase-like gene related to yeast and Arabidopsis genes involved in vesicular transport.

Authors:  C Davies
Journal:  Plant Mol Biol       Date:  1994-02       Impact factor: 4.076

10.  A Rac1 inhibitory peptide suppresses antibody production and paw swelling in the murine collagen-induced arthritis model of rheumatoid arthritis.

Authors:  Joana Rf Abreu; Wendy Dontje; Sarah Krausz; Daphne de Launay; Paula B van Hennik; Anne-Marieke van Stalborch; Jean-Paul Ten Klooster; Marjolein E Sanders; Kris A Reedquist; Margriet J Vervoordeldonk; Peter L Hordijk; Paul P Tak
Journal:  Arthritis Res Ther       Date:  2010-01-06       Impact factor: 5.156
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