Literature DB >> 19047233

Effectiveness of a clinical pathway for the emergency treatment of patients with inborn errors of metabolism.

Dina J Zand1, Kathleen M Brown, Uta Lichter-Konecki, Joyce K Campbell, Vesta Salehi, James M Chamberlain.   

Abstract

OBJECTIVE: The goal was to measure the effectiveness of a clinical pathway for the emergency department care of patients with inborn errors of metabolism.
METHODS: Two years after the implementation of a multidisciplinary clinical pathway for patients with inborn errors of metabolism in our urban, academic, pediatric emergency department, we compared measures of timeliness and effectiveness for patients treated before the pathway with the same measures for patients treated after implementation of the pathway. Measures of timeliness included time to room, time to doctor, time to glucose infusion, and total emergency department length of stay. Measures of clinical effectiveness included the proportion of patients receiving adequate glucose infusions, proportion of patients admitted, inpatient length of stay, and proportion of patients requiring PICU admission.
RESULTS: A total of 214 emergency department visits for patients with inborn errors of metabolism were analyzed, 90 before and 124 after initiation of the pathway. All measures of timeliness of care except total emergency department length of stay demonstrated significant improvement in comparisons of values before and after initiation of the pathway. Measures of clinical effectiveness also demonstrated significant improvements after initiation of the pathway. There was improvement in the proportion of patients who received adequate glucose infusions, with a decrease in the proportion of patients who required admission to the PICU. Emergency department length of stay, inpatient length of stay, and the proportion of patients admitted to the hospital were not affected.
CONCLUSIONS: Most measures of timeliness and 2 measures of effectiveness showed improvement after implementation of an emergency department pathway for patients with inborn errors of metabolism. Therefore, a clinical pathway can improve the emergency care of patients with inborn errors of metabolism.

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Year:  2008        PMID: 19047233     DOI: 10.1542/peds.2008-0205

Source DB:  PubMed          Journal:  Pediatrics        ISSN: 0031-4005            Impact factor:   7.124


  9 in total

Review 1.  The importance of clinical pathways and protocols in pediatric nephrology.

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Journal:  Pediatr Nephrol       Date:  2013-08-18       Impact factor: 3.714

2.  Parent and emergency physician comfort with a system of on-line emergency-focused medical summaries for infants with significant cardiac disease.

Authors:  Lee A Pyles; Margaret Scheid; Michael P McBrady; Kathryn H Hoyman; Molly Hanse; Kathy Jamrozek; Jessica C Hannan; Charles M Baker; Susan J Duval; James H Moller; Claudia I Hines
Journal:  Matern Child Health J       Date:  2011-05

3.  Improving newborn screening laboratory test ordering and result reporting using health information exchange.

Authors:  Stephen M Downs; Peter C van Dyck; Piero Rinaldo; Clement McDonald; R Rodrey Howell; Alan Zuckerman; Gregory Downing
Journal:  J Am Med Inform Assoc       Date:  2010 Jan-Feb       Impact factor: 4.497

4.  Using recommendation to support adaptive clinical pathways.

Authors:  Zhengxing Huang; Xudong Lu; Huilong Duan
Journal:  J Med Syst       Date:  2011-01-05       Impact factor: 4.460

Review 5.  Advances and challenges in the treatment of branched-chain amino/keto acid metabolic defects.

Authors:  Ina Knerr; Natalie Weinhold; Jerry Vockley; K Michael Gibson
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6.  Implementation of a fast-track clinical pathway decreases postoperative length of stay and hospital charges for liver resection.

Authors:  De-Xin Lin; Xuan Li; Qi-Wen Ye; Fen Lin; Lin-Li Li; Qi-Yu Zhang
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7.  Is the critical pathway effective for the treatment of gastric cancer?

Authors:  Sang-Ho Jeong; Moon-Won Yoo; Hong-Man Yoon; Hyuk-Joon Lee; Hye Sung Ahn; Jae-Jin Cho; Hyung-Ho Kim; Kuhn-Uk Lee; Han-Kwang Yang
Journal:  J Korean Surg Soc       Date:  2011-08-03

8.  Clinical pathways for inborn errors of metabolism: warranted and feasible.

Authors:  Serwet Demirdas; Imke N van Kessel; Marjolein J Korndewal; Carla E M Hollak; Hanka Meutgeert; Anja Klaren; Margreet van Rijn; Francjan J van Spronsen; Annet M Bosch
Journal:  Orphanet J Rare Dis       Date:  2013-02-25       Impact factor: 4.123

9.  A generic emergency protocol for patients with inborn errors of metabolism causing fasting intolerance: A retrospective, single-center study and the generation of www.emergencyprotocol.net.

Authors:  Alessandro Rossi; Irene J Hoogeveen; Charlotte M A Lubout; Foekje de Boer; Marieke J Fokkert-Wilts; Iris L Rodenburg; Esther van Dam; Sarah C Grünert; Diego Martinelli; Maurizio Scarpa; Hanka Dekker; Sebastiaan T Te Boekhorst; Francjan J van Spronsen; Terry G J Derks
Journal:  J Inherit Metab Dis       Date:  2021-05-04       Impact factor: 4.982

  9 in total

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