| Literature DB >> 19045840 |
T B Tang1, S Smith, B W Flynn, J T M Stevenson, A M Gundlach, H M Reekie, A F Murray, D Renshaw, B Dhillon, A Ohtori, Y Inoue, J G Terry, A J Walton.
Abstract
A wireless power transfer and communication system based on near-field inductive coupling has been designed and implemented. The feasibility of using such a system to remotely control drug release from an implantable drug delivery system is addressed. The architecture of the wireless system is described and the signal attenuation over distance in both water and phosphate buffered saline is studied. Additionally, the health risk due to exposure to radio frequency (RF) radiation is examined using a biological model. The experimental results demonstrate that the system can trigger the release of drug within 5 s, and that such short exposure to RF radiation does not produce any significant (<or= 1 degrees C) heating in the biological model. The conclusion of the work is that this system could replace a chemical battery in an implantable system, eliminating the risks associated with battery failure and leakage and also allowing more compact designs for applications such as drug delivery.Entities:
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Year: 2008 PMID: 19045840 DOI: 10.1049/iet-nbt:20080001
Source DB: PubMed Journal: IET Nanobiotechnol ISSN: 1751-8741 Impact factor: 1.847