Literature DB >> 1904030

Unexpected side-effects of inhaled steroids: a case report.

K Priftis1, M L Everard, A D Milner.   

Abstract

An asthmatic child is presented who developed a cushingoid appearance with evidence of adrenal suppression and growth impairment while on low dose inhaled topical steroids. When the inhaled steroids were replaced by inhaled sodium cromoglycate his adrenal function recovered while his appearance and growth returned to normal. This report indicates that there are some children who are at risk of developing side-effects on doses of inhaled topical steroids normally considered to be entirely safe.

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Year:  1991        PMID： 1904030     DOI： 10.1007/bf02093730

Source DB:  PubMed          Journal:  Eur J Pediatr        ISSN： 0340-6199            Impact factor:   3.183


  9 in total

1.  Adrenal function in children with bronchial asthma treated with beclomethasone dipropionate or budesonide.

Authors:  H Bisgaard; M Damkjaer Nielsen; B Andersen; P Andersen; N Foged; G Fuglsang; A Høst; C Leth; M Pedersen; I Pelck
Journal:  J Allergy Clin Immunol       Date:  1988-06       Impact factor: 10.793

2.  Adrenal function in asthma.

Authors:  K Priftis; A D Milner; E Conway; J W Honour
Journal:  Arch Dis Child       Date:  1990-08       Impact factor: 3.791

3.  Overt glucocorticoid excess due to inhaled corticosteroid therapy.

Authors:  G A Hollman; D B Allen
Journal:  Pediatrics       Date:  1988-03       Impact factor: 7.124

4.  Development of new glucocorticosteroids with a very high ratio between topical and systemic activities.

Authors:  R Brattsand; A Thalén; K Roempke; L Källström; E Gruvstad
Journal:  Eur J Respir Dis Suppl       Date:  1982

5.  Adrenocortical function in children on high-dose steroid aerosol therapy. Results of serum cortisol, ACTH stimulation test and 24 hour urinary free cortical excretion.

Authors:  P Prahl; T Jensen; H Bjerregaard-Andersen
Journal:  Allergy       Date:  1987-10       Impact factor: 13.146

6.  Biotransformation of the topical glucocorticoids budesonide and beclomethasone 17 alpha,21-dipropionate in human liver and lung homogenate.

Authors:  P Andersson; A Ryrfeldt
Journal:  J Pharm Pharmacol       Date:  1984-11       Impact factor: 3.765

7.  Effect of inhaled beclomethasone dipropionate on hypothalamic-pituitary-adrenal axis function in children with asthma.

Authors:  D E Goldstein; P König
Journal:  Pediatrics       Date:  1983-07       Impact factor: 7.124

8.  A three- to five-year follow-up of the use of the aerosol steroid, beclomethasone dipropionate, in childhood asthma.

Authors:  S Godfrey; L Balfour-Lynn; M Tooley
Journal:  J Allergy Clin Immunol       Date:  1978-12       Impact factor: 10.793

9.  Nocturnal adrenal suppression in asthmatic children taking inhaled beclomethasone dipropionate.

Authors:  C M Law; J L Marchant; J W Honour; M A Preece; J O Warner
Journal:  Lancet       Date:  1986-04-26       Impact factor: 79.321
  9 in total
  8 in total

1.  Adrenal function and high dose inhaled corticosteroids for asthma.

Authors:  P K Yiallouros; A D Milner; E Conway; J W Honour
Journal:  Arch Dis Child       Date:  1997-05       Impact factor: 3.791

Review 2.  Management of carcinomas of the upper gastrointestinal tract.

Authors:  P Ellis; D Cunningham
Journal:  BMJ       Date:  1994-03-26

Review 3.  Inhaled corticosteroid therapy in children: an assessment of the potential for side effects.

Authors:  G Russell
Journal:  Thorax       Date:  1994-12       Impact factor: 9.139

4.  Rapidly developing Cushing syndrome in a 4-year-old patient during combined treatment with itraconazole and inhaled budesonide.

Authors:  Elke De Wachter; Jesse Vanbesien; Iris De Schutter; Anne Malfroot; Jean De Schepper
Journal:  Eur J Pediatr       Date:  2003-04-26       Impact factor: 3.183

Review 5.  Inhaled corticosteroids in children. Is there a 'safe' dosage?

Authors:  A L Boner; G L Piacentini
Journal:  Drug Saf       Date:  1993-07       Impact factor: 5.606

Review 6.  Glucocorticosteroid-induced spinal osteoporosis: scientific update on pathophysiology and treatment.

Authors:  Albrecht W Popp; Juerg Isenegger; Elizabeth M Buergi; Ulrich Buergi; Kurt Lippuner
Journal:  Eur Spine J       Date:  2006-07       Impact factor: 3.134

7.  Once-Daily Fluticasone Propionate is as Effective as Twice-Daily Treatment in Stable, Mild-to-Moderate Childhood Asthma.

Authors:  Ian G C Hodges; Thelma A Netherway
Journal:  Clin Drug Investig       Date:  2005       Impact factor: 2.859

8.  Impact of inhalation therapy on oral health.

Authors:  Navneet Godara; Ramya Godara; Megha Khullar
Journal:  Lung India       Date:  2011-10
  8 in total

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