Literature DB >> 19039083

Acrolein environmental levels and potential for human exposure.

O Faroon1, N Roney, J Taylor, A Ashizawa, M H Lumpkin, D J Plewak.   

Abstract

This article provides environmental information on acrolein including environmental fate, potential for human exposure, analytical methods, and a listing of regulations and advisories. Acrolein may be released to the environment in emissions and effluents from its manufacturing and use facilities, in emissions from combustion processes (including cigarette smoking and combustion of petrochemical fuels), from direct application to water and waste water as a slimicide and aquatic herbicide, as a photooxidation product of various hydrocarbon pollutants found in air (including propylene and 1,3-butadiene), and from land disposal of some organic waste materials. Acrolein is a reactive compound and is unstable in the environment. The general population may be exposed to acrolein through inhalation of contaminated air and through ingestion of certain foods. Important sources of acrolein exposure are via inhalation of tobacco smoke and environmental tobacco smoke and via the overheating of fats contained in all living matter. There is potential for exposure to acrolein in many occupational settings as the result of its varied uses and its formation during the combustion and pyrolysis of materials such as wood, petrochemical fuels, and plastics.

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Year:  2008        PMID: 19039083     DOI: 10.1177/0748233708098124

Source DB:  PubMed          Journal:  Toxicol Ind Health        ISSN: 0748-2337            Impact factor:   2.273


  24 in total

1.  Inhalation of the reactive aldehyde acrolein promotes antigen sensitization to ovalbumin and enhances neutrophilic inflammation.

Authors:  Edmund O'Brien; Page C Spiess; Aida Habibovic; Milena Hristova; Robert A Bauer; Matthew J Randall; Matthew E Poynter; Albert van der Vliet
Journal:  J Immunotoxicol       Date:  2015-04-15       Impact factor: 3.000

Review 2.  Environmental Aldehyde Sources and the Health Implications of Exposure.

Authors:  Pritam Sinharoy; Stacy L McAllister; Megana Vasu; Eric R Gross
Journal:  Adv Exp Med Biol       Date:  2019       Impact factor: 2.622

3.  Endothelial dysfunction and claudin 5 regulation during acrolein-induced lung injury.

Authors:  An Soo Jang; Vincent J Concel; Kiflai Bein; Kelly A Brant; Shannen Liu; Hannah Pope-Varsalona; Richard A Dopico; Y P Peter Di; Daren L Knoell; Aaron Barchowsky; George D Leikauf
Journal:  Am J Respir Cell Mol Biol       Date:  2010-06-04       Impact factor: 6.914

4.  Subacute acrolein exposure to rat larynx in vivo.

Authors:  Xinxin Liu; Abigail C Durkes; William Schrock; Wei Zheng; M Preeti Sivasankar
Journal:  Laryngoscope       Date:  2018-12-24       Impact factor: 3.325

5.  Matrix metalloproteinase-14 mediates a phenotypic shift in the airways to increase mucin production.

Authors:  Hitesh S Deshmukh; Anne McLachlan; Jeffrey J Atkinson; William D Hardie; Thomas R Korfhagen; Maggie Dietsch; Yang Liu; Peter Y P Di; Scott C Wesselkamper; Michael T Borchers; George D Leikauf
Journal:  Am J Respir Crit Care Med       Date:  2009-08-06       Impact factor: 21.405

Review 6.  Mechanisms of soft and hard electrophile toxicities.

Authors:  Richard M LoPachin; Brian C Geohagen; Lars U Nordstroem
Journal:  Toxicology       Date:  2019-02-28       Impact factor: 4.221

7.  Ion transport mechanisms for smoke inhalation-injured airway epithelial barrier.

Authors:  Jianjun Chang; Zaixing Chen; Runzhen Zhao; Hong-Guang Nie; Hong-Long Ji
Journal:  Cell Biol Toxicol       Date:  2020-06-25       Impact factor: 6.691

8.  Mechanisms Underlying Acrolein-Mediated Inhibition of Chromatin Assembly.

Authors:  Lei Fang; Danqi Chen; Clinton Yu; Hongjie Li; Jason Brocato; Lan Huang; Chunyuan Jin
Journal:  Mol Cell Biol       Date:  2016-11-14       Impact factor: 4.272

9.  Cigarette smoke component acrolein modulates chromatin assembly by inhibiting histone acetylation.

Authors:  Danqi Chen; Lei Fang; Hongjie Li; Moon-shong Tang; Chunyuan Jin
Journal:  J Biol Chem       Date:  2013-06-14       Impact factor: 5.157

10.  Joint toxic effects of the type-2 alkene electrophiles.

Authors:  Lihai Zhang; Brian C Geohagen; Terrence Gavin; Richard M LoPachin
Journal:  Chem Biol Interact       Date:  2016-06-08       Impact factor: 5.192

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