Ranee Thakar1, Susan Ayers, Rashmi Srivastava, Isaac Manyonda. 1. From the Department of Obstetrics and Gynecology, Mayday University Hospital, Croydon, United Kingdom; the Department of Health Psychology, University of Sussex, Brighton, United Kingdom; and the Department of Obstetrics and Gynecology, St George's University of London, London, United Kingdom.
Abstract
OBJECTIVE: : To evaluate the long-term outcomes in women who underwenttotal abdominal hysterectomy (TAH) and subtotal abdominal hysterectomy (sub-TAH). METHODS: : Two hundred seventy-nine women between 7 and 11 years (mean 9 years) of follow-up who participated in a previously published randomized, double-blind, multicenter trial comparing TAH and sub-TAH were invited to complete questionnaires used in the previous study to assess quality of life and pelvic organ function. RESULTS: : Sixty-five percent of the women (90 TAH and 91 sub-TAH) completed the study. There were no significant differences in quality of life, mental health, and pelvic organ function between TAH and sub-TAH. Urinary and bowel function variables did not change significantly over time, but significant decreases were found in a range of sexual function parameters, pain, and role limitations due to emotional problems in both the groups. CONCLUSION: : There were no long-term differences in outcomes between TAH and sub-TAH. The lack of a detrimental effect on bowel and urinary function seen at 12 months was maintained. The deterioration in sexual function is likely to be due to the climacteric. CLINICAL TRIAL REGISTRATION: : ClinicalTrials.gov, www.clinicaltrials.gov, NCT00750035 LEVEL OF EVIDENCE: : I.
RCT Entities:
OBJECTIVE: : To evaluate the long-term outcomes in women who underwent total abdominal hysterectomy (TAH) and subtotal abdominal hysterectomy (sub-TAH). METHODS: : Two hundred seventy-nine women between 7 and 11 years (mean 9 years) of follow-up who participated in a previously published randomized, double-blind, multicenter trial comparing TAH and sub-TAH were invited to complete questionnaires used in the previous study to assess quality of life and pelvic organ function. RESULTS: : Sixty-five percent of the women (90 TAH and 91 sub-TAH) completed the study. There were no significant differences in quality of life, mental health, and pelvic organ function between TAH and sub-TAH. Urinary and bowel function variables did not change significantly over time, but significant decreases were found in a range of sexual function parameters, pain, and role limitations due to emotional problems in both the groups. CONCLUSION: : There were no long-term differences in outcomes between TAH and sub-TAH. The lack of a detrimental effect on bowel and urinary function seen at 12 months was maintained. The deterioration in sexual function is likely to be due to the climacteric. CLINICAL TRIAL REGISTRATION: : ClinicalTrials.gov, www.clinicaltrials.gov, NCT00750035 LEVEL OF EVIDENCE: : I.
Authors: Gabriel Francisco Aleixo; Marcelo C M Fonseca; Maria Augusta Tezelli Bortolini; Luiz Gustavo O Brito; Rodrigo A Castro Journal: Int Urogynecol J Date: 2018-11-22 Impact factor: 2.894