| Literature DB >> 19036690 |
Edward Kim1, John M Hwang, Julio Garcia-Aguilar.
Abstract
Local excision is an alternative approach to radical proctectomy for rectal cancer, but from an oncologic standpoint, it is a compromise, and its role remains controversial. Careful patient selection is essential because local excision is generally considered only for early rectal cancer with no evidence of nodal metastasis, parameters that can be predicted by clinical examination, and various radiologic modalities with variable accuracy. In this review, we present the literature evaluating the oncologic adequacy of local excision, including transanal endoscopic microsurgery and the results of salvage surgery after local excision. An overview of local excision in the context of perioperative adjuvant therapies is included. Finally, we suggest a treatment algorithm for local excision in rectal cancer.Entities:
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Year: 2008 PMID: 19036690 DOI: 10.3816/CCC.2008.n.050
Source DB: PubMed Journal: Clin Colorectal Cancer ISSN: 1533-0028 Impact factor: 4.481