| Literature DB >> 1903132 |
N T Ralphs1, S Garrett, R Morse, J B Cookson, P W Andrew, G J Boulnois.
Abstract
A 1.5 kb EcoRI-BamHI restriction fragment from Mycobacterium tuberculosis was found to hybridize specifically with genomic DNA from M. tuberculosis-complex organisms. Primers were designed from the terminal sequences of this fragment and used to amplify uniquely M. tuberculosis-group DNA in a polymerase chain reaction. It is suggested that a combination of these primers and probe will prove a useful tool for the early diagnosis of tuberculous infections.Entities:
Mesh：
Substances：
Year: 1991 PMID： 1903132 DOI： 10.1111/j.1365-2672.1991.tb02928.x
Source DB: PubMed Journal: J Appl Bacteriol ISSN： 0021-8847