Paulino Vigil-De Gracia1. 1. Critical Care Unit, Department of Obstetrics and Gynecology, Caja de Seguro Social, Panama, Panama.
Abstract
OBJECTIVE: To evaluate maternal deaths associated with eclampsia, HELLP syndrome, and the concurrence of these conditions. METHOD: A review of Medline studies reporting maternal deaths associated with eclampsia or HELLP syndrome published in English, Spanish, and Portuguese between 1995 and June 2008. RESULTS: A total of 304 deaths were identified: 100 due to eclampsia, 117 due to eclampsia/HELLP, and 87 associated with HELLP syndrome. Of the total deaths, 71.3% of women had seizures and 67.1% developed HELLP syndrome. In high-income countries 3.9% of deaths were due to eclampsia without HELLP syndrome, while in low-income countries this figure was 42.5% (P<0.0001). The presence of HELLP syndrome in the women who died of eclampsia was 90.6% (29/32) in high-income countries compared with 47.6% (88/185) in low-income countries (P<0.001). CONCLUSION: Concurrent eclampsia and HELLP syndrome was diagnosed in 5-6 out of 10 deaths associated with eclampsia or HELLP syndrome in this review.
OBJECTIVE: To evaluate maternal deaths associated with eclampsia, HELLP syndrome, and the concurrence of these conditions. METHOD: A review of Medline studies reporting maternal deaths associated with eclampsia or HELLP syndrome published in English, Spanish, and Portuguese between 1995 and June 2008. RESULTS: A total of 304 deaths were identified: 100 due to eclampsia, 117 due to eclampsia/HELLP, and 87 associated with HELLP syndrome. Of the total deaths, 71.3% of women had seizures and 67.1% developed HELLP syndrome. In high-income countries 3.9% of deaths were due to eclampsia without HELLP syndrome, while in low-income countries this figure was 42.5% (P<0.0001). The presence of HELLP syndrome in the women who died of eclampsia was 90.6% (29/32) in high-income countries compared with 47.6% (88/185) in low-income countries (P<0.001). CONCLUSION: Concurrent eclampsia and HELLP syndrome was diagnosed in 5-6 out of 10 deaths associated with eclampsia or HELLP syndrome in this review.
Authors: Luise Erpenbeck; Melanie Demers; Zsuzsanna K Zsengellér; Maureen Gallant; Stephen M Cifuni; Isaac E Stillman; S Ananth Karumanchi; Denisa D Wagner Journal: J Am Soc Nephrol Date: 2015-06-02 Impact factor: 10.121
Authors: Gianluca Raffaello Damiani; Viviana Merola; Mario Barnaba; Stefano Landi; Gennaro Cormio; Antonio Pellegrino Journal: Case Rep Med Date: 2014-08-31
Authors: Jeffrey Michael Smith; Richard F Lowe; Judith Fullerton; Sheena M Currie; Laura Harris; Erica Felker-Kantor Journal: BMC Pregnancy Childbirth Date: 2013-02-05 Impact factor: 3.007