Literature DB >> 19024009

Comparative analysis of secretion of S100A4 metastatic marker by immune and tumor cells.

E A Dukhanina1, T I Lukyanova, E A Romanova, A S Dukhanin, L P Sashchenko.   

Abstract

S100A4 protein is present in low concentrations (2.1-15.7 ng/10(6) cells) in lymphocyte and neutrophil culture medium. Addition of stimulants to the cells did not lead to an appreciable increase in the content of this protein. The initial content of S100A4 is significantly higher (92-447 ng/10(6) cells) in culture media of highly metastatic KSML-100 adenocarcinoma and M3 and B16 melanoma cells. The release of S100A4 by these cells significantly increased after addition of lymphocytes and Tag7/Hsp70 cytotoxic complex. Repeated injection of antibodies to S100A4 to mice with transplanted M3 melanoma inhibited tumor growth.

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Year:  2008        PMID： 19024009     DOI： 10.1007/s10517-008-0003-z

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN： 0007-4888            Impact factor:   0.804


  8 in total

1.  The metastasis-promoting S100A4 protein confers neuroprotection in brain injury.

Authors:  Oksana Dmytriyeva; Stanislava Pankratova; Sylwia Owczarek; Katrin Sonn; Vladislav Soroka; Christina M Ridley; Alexander Marsolais; Marcos Lopez-Hoyos; Noona Ambartsumian; Eugene Lukanidin; Elisabeth Bock; Vladimir Berezin; Darya Kiryushko
Journal:  Nat Commun       Date:  2012       Impact factor: 14.919

2.  The role of S100A4 protein in anticancer cytotoxicity: its presence is required on the surface of CD4+CD25+PGRPs+S100A4+ lymphocyte and undesirable on the surface of target cells.

Authors:  E A Dukhanina; T I Lukyanova; A S Dukhanin; S G Georgieva
Journal:  Cell Cycle       Date:  2018-02-08       Impact factor: 4.534

3.  Triple-negative and triple-positive breast cancer cells reciprocally control their growth and migration via the S100A4 pathway.

Authors:  Elena A Dukhanina; Tatiana N Portseva; Alexander S Dukhanin; Sofia G Georgieva
Journal:  Cell Adh Migr       Date:  2022-12       Impact factor: 3.255

4.  A new role for PGRP-S (Tag7) in immune defense: lymphocyte migration is induced by a chemoattractant complex of Tag7 with Mts1.

Authors:  E A Dukhanina; T I Lukyanova; E A Romanova; V Guerriero; N V Gnuchev; G P Georgiev; D V Yashin; L P Sashchenko
Journal:  Cell Cycle       Date:  2015       Impact factor: 4.534

5.  Oct-1 modifies S100A4 exchange between intra- and extracellular compartments in Namalwa cells and increases their sensitivity to glucocorticoids.

Authors:  Elena A Dukhanina; Tatiana N Portseva; Elizaveta V Pankratova; Natalia V Soshnikova; Alexander G Stepchenko; Alexander S Dukhanin; Sofia G Georgieva
Journal:  Cell Cycle       Date:  2016-04-20       Impact factor: 4.534

6.  Proteomic and systems biology analysis of monocytes exposed to securinine, a GABA(A) receptor antagonist and immune adjuvant.

Authors:  Matt Shipman; Kirk Lubick; David Fouchard; Rajani Guram; Paul Grieco; Mark Jutila; Edward A Dratz
Journal:  PLoS One       Date:  2012-09-13       Impact factor: 3.240

7.  Anti-S100A4 Antibody Therapy Is Efficient in Treating Aggressive Prostate Cancer and Reversing Immunosuppression: Serum and Biopsy S100A4 as a Clinical Predictor.

Authors:  Arsheed A Ganaie; Adrian P Mansini; Tabish Hussain; Arpit Rao; Hifzur R Siddique; Ashraf Shabaneh; Marina G Ferrari; Paari Murugan; Jörg Klingelhöfer; Jinhua Wang; Noona Ambartsumian; Christopher A Warlick; Badrinath R Konety; Mohammad Saleem
Journal:  Mol Cancer Ther       Date:  2020-09-30       Impact factor: 6.009

8.  The S100A4 Protein Signals through the ErbB4 Receptor to Promote Neuronal Survival.

Authors:  Stanislava Pankratova; Jorg Klingelhofer; Oksana Dmytriyeva; Sylwia Owczarek; Alexander Renziehausen; Nelofer Syed; Alexandra E Porter; David T Dexter; Darya Kiryushko
Journal:  Theranostics       Date:  2018-07-01       Impact factor: 11.556
  8 in total

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