Literature DB >> 19023805

1-O-Substituted derivatives of murrayafoline A and their antifungal properties.

N M Cuong1, H Wilhelm, A Porzel, N Arnold, L Wessjohann.   

Abstract

The synthesis of some 1-oxygenated derivatives of murrayafoline A (1) and their antifungal properties is reported. Three derivatives, 1-hydroxy-3-methyl-9H-carbazole (2), 1-(3-methylbut-2-enyloxy)-3-methyl-9H-carbazole (3) and 1-(2,3,4,6-tetra-O-acetyl-alpha-D-O-glucopyranosyl)-3-methyl-9H-carbazole (4) of murrayafoline A were synthesized. Compounds 1 and 2 exhibited strong fungicidal activity against Cladosporium cucumerinum at the dose of 12.5 microg.

Entities:  

Mesh：

Substances：

Year:  2008        PMID： 19023805     DOI： 10.1080/14786410802006033

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN： 1478-6419            Impact factor:   2.861


  3 in total

1.  Potential Antimicrobial Isopropanol-Conjugated Carbazole Azoles as Dual Targeting Inhibitors of Enterococcus faecalis.

Authors:  Yuan Zhang; Vijai Kumar Reddy Tangadanchu; Yu Cheng; Ren-Guo Yang; Jian-Mei Lin; Cheng-He Zhou
Journal:  ACS Med Chem Lett       Date:  2018-02-05       Impact factor: 4.345

2.  Design, Synthesis and In Vitro Characterization of Novel Antimicrobial Agents Based on 6-Chloro-9H-carbazol Derivatives and 1,3,4-Oxadiazole Scaffolds.

Authors:  Alexandra T Bordei Telehoiu; Diana C Nuță; Miron T Căproiu; Florea Dumitrascu; Irina Zarafu; Petre Ioniță; Carmellina D Bădiceanu; Speranța Avram; Mariana C Chifiriuc; Coralia Bleotu; Carmen Limban
Journal:  Molecules       Date:  2020-01-09       Impact factor: 4.411

3.  Murrayafoline A Induces a G0/G1-Phase Arrest in Platelet-Derived Growth Factor-Stimulated Vascular Smooth Muscle Cells.

Authors:  Joo-Hui Han; Yohan Kim; Sang-Hyuk Jung; Jung-Jin Lee; Hyun-Soo Park; Gyu-Yong Song; Nguyen Manh Cuong; Young Ho Kim; Chang-Seon Myung
Journal:  Korean J Physiol Pharmacol       Date:  2015-08-20       Impact factor: 2.016
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.