| Literature DB >> 19022751 |
Abstract
The identification of transcription factors to induce pluripotency directly in somatic cells has given researchers a unique platform on which to dissect the mechanisms underlying epigenetic reprogramming. In addition, induced pluripotent stem (iPS) cells have enabled the derivation of patient-specific cells for the study and potential treatment of a variety of diseases. Here, we discuss recent discoveries in the reprogramming field including work from our own laboratory.Entities:
Mesh:
Substances:
Year: 2008 PMID: 19022751 DOI: 10.1101/sqb.2008.73.017
Source DB: PubMed Journal: Cold Spring Harb Symp Quant Biol ISSN: 0091-7451