| Literature DB >> 19022293 |
S Zainah1, A H Abdul Wahab, M Mariam, M K Fauziah, A H Khairul, I Roslina, A Sairulakhma, S S Kadimon, M S Mat Jais, K B Chua.
Abstract
The performance of a commercial immunochromatography test for rapid detection of dengue NS1 antigen present in serum or plasma of patients was evaluated against a commercial dengue NS1 antigen-capture ELISA. The rapid immunochromatography test gave an overall sensitivity of 90.4% with a specificity of 99.5%. The sensitivity was highest for serum samples from which virus was isolated (96.3%) and lowest for those from which virus was not isolated and RT-PCR was negative (76.4%). The sensitivity was significantly higher for serum samples from patients with acute primary dengue (92.3%) than those from patients with acute secondary dengue (79.1%). The positive predictive value and negative predictive value of this commercial immunochromatography test were 99.6% and 87.9% respectively.Entities:
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Year: 2008 PMID： 19022293 DOI： 10.1016/j.jviromet.2008.10.016
Source DB: PubMed Journal: J Virol Methods ISSN： 0166-0934 Impact factor: 2.014