Literature DB >> 19015361

Klebsiella pneumoniae OmpA confers resistance to antimicrobial peptides.

Enrique Llobet1, Catalina March, Paloma Giménez, José A Bengoechea.   

Abstract

A Klebsiella pneumoniae ompA mutant was more susceptible to antimicrobial peptides (APs) than the wild type. Susceptibility did not result from surface changes other than the absence of OmpA. Our data suggest that OmpA is implicated in the activation of yet-unknown systems dedicated to ameliorating AP cytotoxicity.

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Year:  2008        PMID： 19015361      PMCID： PMC2612193          DOI： 10.1128/AAC.00657-08

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  41 in total

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  31 in total

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