Literature DB >> 9033483

Peptide antibiotics.

R E Hancock1.   

Abstract

The era of the "classical antibiotic" may be over. The emergence of resistance has seen to that. Yet no truly novel class of antibacterial agent has come on the market in the past 30 years. Currently there is great interest in peptide antibiotics, especially the cationic peptides. Thousands of such molecules have been synthesised and just a few are entering clinical trials. Because they kill bacteria quickly by the physical disruption of cell membranes, peptide antibiotics may not face the rapid emergence of resistance.

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Year:  1997        PMID: 9033483     DOI: 10.1016/S0140-6736(97)80051-7

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  314 in total

1.  The "pro" sequence of the sporulation-specific sigma transcription factor sigma(E) directs it to the mother cell side of the sporulation septum.

Authors:  J Ju; W G Haldenwang
Journal:  J Bacteriol       Date:  1999-10       Impact factor: 3.490

2.  Anticandida activity is retained in P-113, a 12-amino-acid fragment of histatin 5.

Authors:  D M Rothstein; P Spacciapoli; L T Tran; T Xu; F D Roberts; M Dalla Serra; D K Buxton; F G Oppenheim; P Friden
Journal:  Antimicrob Agents Chemother       Date:  2001-05       Impact factor: 5.191

3.  MICs of mutacin B-Ny266, nisin A, vancomycin, and oxacillin against bacterial pathogens.

Authors:  M Mota-Meira; G LaPointe; C Lacroix; M C Lavoie
Journal:  Antimicrob Agents Chemother       Date:  2000-01       Impact factor: 5.191

4.  In vitro susceptibility tests for cationic peptides: comparison of broth microdilution methods for bacteria that grow aerobically.

Authors:  A Giacometti; O Cirioni; F Barchiesi; M S Del Prete; M Fortuna; F Caselli; G Scalise
Journal:  Antimicrob Agents Chemother       Date:  2000-06       Impact factor: 5.191

5.  Improved derivatives of bactenecin, a cyclic dodecameric antimicrobial cationic peptide.

Authors:  M Wu; R E Hancock
Journal:  Antimicrob Agents Chemother       Date:  1999-05       Impact factor: 5.191

Review 6.  Host defence (cationic) peptides: what is their future clinical potential?

Authors:  R E Hancock
Journal:  Drugs       Date:  1999-04       Impact factor: 9.546

Review 7.  A neutrophil-derived anti-infective molecule: bactericidal/permeability-increasing protein.

Authors:  O Levy
Journal:  Antimicrob Agents Chemother       Date:  2000-11       Impact factor: 5.191

8.  Short-term exposure to membrane-active antibiotics inhibits Cryptosporidium parvum infection in cell culture.

Authors:  A Giacometti; O Cirioni; M S Del Prete; F Barchiesi; G Scalise
Journal:  Antimicrob Agents Chemother       Date:  2000-12       Impact factor: 5.191

9.  Rapid two-step procedure for large-scale purification of pediocin-like bacteriocins and other cationic antimicrobial peptides from complex culture medium.

Authors:  Marianne Uteng; Håvard Hildeng Hauge; Ilia Brondz; Jon Nissen-Meyer; Gunnar Fimland
Journal:  Appl Environ Microbiol       Date:  2002-02       Impact factor: 4.792

10.  Reducing mortality in Salmonella enterica serovar Typhimurium-infected mice with a tripeptidic serum fraction.

Authors:  Todd A Parker; Kenneth O Willeford; Suzanne Parker; Karyl Buddington
Journal:  Antimicrob Agents Chemother       Date:  2002-06       Impact factor: 5.191

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