Literature DB >> 19013269

The safety on the TCR trigger.

Michael S Kuhns1, Mark M Davis.   

Abstract

In this issue, Xu et al. (2008) provide evidence for a new mechanism of T cell receptor regulation. Prior to activation, basic residues in the cytoplasmic domain of the signaling subunits of the T cell receptor associate with the plasma membrane such that the key signaling tyrosines are sequestered in the bilayer.

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Year:  2008        PMID： 19013269      PMCID： PMC2905657          DOI： 10.1016/j.cell.2008.10.033

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  10 in total

1.  Phosphorylation of T cell receptor zeta is regulated by a lipid dependent folding transition.

Authors:  D Aivazian; L J Stern
Journal:  Nat Struct Biol       Date:  2000-11

2.  The serine and threonine residues in the Ig-alpha cytoplasmic tail negatively regulate immunoreceptor tyrosine-based activation motif-mediated signal transduction.

Authors:  R Müller; J Wienands; M Reth
Journal:  Proc Natl Acad Sci U S A       Date:  2000-07-18       Impact factor: 11.205

Review 3.  The TCR triggering puzzle.

Authors:  P A van der Merwe
Journal:  Immunity       Date:  2001-06       Impact factor: 31.745

Review 4.  Common themes in the assembly and architecture of activating immune receptors.

Authors:  Matthew E Call; Kai W Wucherpfennig
Journal:  Nat Rev Immunol       Date:  2007-11       Impact factor: 53.106

5.  Lipid-binding activity of intrinsically unstructured cytoplasmic domains of multichain immune recognition receptor signaling subunits.

Authors:  Alexander B Sigalov; Dikran A Aivazian; Vladimir N Uversky; Lawrence J Stern
Journal:  Biochemistry       Date:  2006-12-19       Impact factor: 3.162

6.  Antigen receptor tail clue.

Authors:  M Reth
Journal:  Nature       Date:  1989-03-30       Impact factor: 49.962

Review 7.  Lipid signaling and the modulation of surface charge during phagocytosis.

Authors:  Tony Yeung; Sergio Grinstein
Journal:  Immunol Rev       Date:  2007-10       Impact factor: 12.988

8.  Scalable signaling mediated by T cell antigen receptor-CD3 ITAMs ensures effective negative selection and prevents autoimmunity.

Authors:  Jeff Holst; Haopeng Wang; Kelly Durick Eder; Creg J Workman; Kelli L Boyd; Zachary Baquet; Harvir Singh; Karen Forbes; Andrzej Chruscinski; Richard Smeyne; Nicolai S C van Oers; Paul J Utz; Dario A A Vignali
Journal:  Nat Immunol       Date:  2008-05-11       Impact factor: 25.606

9.  Regulation of T cell receptor activation by dynamic membrane binding of the CD3epsilon cytoplasmic tyrosine-based motif.

Authors:  Chenqi Xu; Etienne Gagnon; Matthew E Call; Jason R Schnell; Charles D Schwieters; Christopher V Carman; James J Chou; Kai W Wucherpfennig
Journal:  Cell       Date:  2008-11-14       Impact factor: 41.582

10.  The membrane-proximal portion of CD3 epsilon associates with the serine/threonine kinase GRK2.

Authors:  Laura M DeFord-Watts; Jennifer A Young; Lisa A Pitcher; Nicolai S C van Oers
Journal:  J Biol Chem       Date:  2007-04-09       Impact factor: 5.157
  10 in total
  25 in total

1.  The SCHOOL of nature: I. Transmembrane signaling.

Authors:  Alexander B Sigalov
Journal:  Self Nonself       Date:  2010-01

2.  Membrane binding of intrinsically disordered proteins: Critical importance of an appropriate membrane model.

Authors:  Alexander B Sigalov
Journal:  Self Nonself       Date:  2010-02-17

3.  Basal and antigen-induced exposure of the proline-rich sequence in CD3ε.

Authors:  Javier de la Cruz; Travis Kruger; Christopher A Parks; Robert L Silge; Nicolai S C van Oers; Immanuel F Luescher; Adam G Schrum; Diana Gil
Journal:  J Immunol       Date:  2011-01-12       Impact factor: 5.422

4.  The SCHOOL of nature: II. Protein order, disorder and oligomericity in transmembrane signaling.

Authors:  Alexander B Sigalov
Journal:  Self Nonself       Date:  2010-02-22

Review 5.  A view into the blind spot: solution NMR provides new insights into signal transduction across the lipid bilayer.

Authors:  Matthew E Call; James J Chou
Journal:  Structure       Date:  2010-12-08       Impact factor: 5.006

6.  Conformational states of the kinase Lck regulate clustering in early T cell signaling.

Authors:  Jérémie Rossy; Dylan M Owen; David J Williamson; Zhengmin Yang; Katharina Gaus
Journal:  Nat Immunol       Date:  2012-12-02       Impact factor: 25.606

7.  Ca2+ regulates T-cell receptor activation by modulating the charge property of lipids.

Authors:  Xiaoshan Shi; Yunchen Bi; Wei Yang; Xingdong Guo; Yan Jiang; Chanjuan Wan; Lunyi Li; Yibing Bai; Jun Guo; Yujuan Wang; Xiangjun Chen; Bo Wu; Hongbin Sun; Wanli Liu; Junfeng Wang; Chenqi Xu
Journal:  Nature       Date:  2012-12-02       Impact factor: 49.962

8.  Membrane binding mode of intrinsically disordered cytoplasmic domains of T cell receptor signaling subunits depends on lipid composition.

Authors:  Alexander B Sigalov; Gregory M Hendricks
Journal:  Biochem Biophys Res Commun       Date:  2009-09-04       Impact factor: 3.575

9.  Membrane association of the CD3ε signaling domain is required for optimal T cell development and function.

Authors:  Matthew L Bettini; Clifford Guy; Pradyot Dash; Kate M Vignali; David E Hamm; Jessica Dobbins; Etienne Gagnon; Paul G Thomas; Kai W Wucherpfennig; Dario A A Vignali
Journal:  J Immunol       Date:  2014-06-04       Impact factor: 5.422

10.  Genetic fingerprinting of the development and progression of T-cell lymphoma in a murine model of atypical myeloproliferative disorder initiated by the ZNF198-fibroblast growth factor receptor-1 chimeric tyrosine kinase.

Authors:  Mingqiang Ren; Xiurong Li; John K Cowell
Journal:  Blood       Date:  2009-06-08       Impact factor: 22.113
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