| Literature DB >> 19013267 |
Simona Polo1, Pier Paolo Di Fiore.
Abstract
In response to environmental cues, certain plasma membrane proteins are ubiquitinated, signaling their endocytosis and degradation. In the budding yeast, a single enzyme, Rsp5, is charged with this task. Lin et al. (2008) now identify an arrestin-related family of Rsp5 adaptor proteins called ARTs that confer specificity on the ubiquitination of plasma membrane proteins and contribute to the maintenance of the correct cell surface protein repertoire.Entities:
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Year: 2008 PMID： 19013267 DOI： 10.1016/j.cell.2008.10.032
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582