Literature DB >> 19011749

Medium- and short-chain dehydrogenase/reductase gene and protein families : Three-dimensional structures of MDR alcohol dehydrogenases.

H Eklund1, S Ramaswamy.   

Abstract

In this report we describe the main features of the initially determined alcohol dehydrogenase, that of horse liver, relate this to the human enzyme structures and review recent structural studies on mutants and new complexes of the enzymes. We further review the structure of a bacterial alcohol dehydrogenase to arrive at a coherent picture of medium-chain dehydrogenase/reductase alcohol dehydrogenases in general.

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Year:  2008        PMID: 19011749     DOI: 10.1007/s00018-008-8589-x

Source DB:  PubMed          Journal:  Cell Mol Life Sci        ISSN: 1420-682X            Impact factor:   9.261


  17 in total

1.  Atomic-resolution structures of horse liver alcohol dehydrogenase with NAD(+) and fluoroalcohols define strained Michaelis complexes.

Authors:  Bryce V Plapp; S Ramaswamy
Journal:  Biochemistry       Date:  2012-05-01       Impact factor: 3.162

2.  Geraniol and geranial dehydrogenases induced in anaerobic monoterpene degradation by Castellaniella defragrans.

Authors:  Frauke Lüddeke; Annika Wülfing; Markus Timke; Frauke Germer; Johanna Weber; Aytac Dikfidan; Tobias Rahnfeld; Dietmar Linder; Anke Meyerdierks; Jens Harder
Journal:  Appl Environ Microbiol       Date:  2012-01-27       Impact factor: 4.792

3.  Crystallization and preliminary X-ray crystallographic analysis of the putative NADP(H)-dependent oxidoreductase YncB from Vibrio vulnificus.

Authors:  Min-Kyu Kim; Young Jun An; Chang-Sook Jeong; Sun-Shin Cha
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2012-08-31

4.  Structure-guided engineering of Lactococcus lactis alcohol dehydrogenase LlAdhA for improved conversion of isobutyraldehyde to isobutanol.

Authors:  Xiang Liu; Sabine Bastian; Christopher D Snow; Eric M Brustad; Tatyana E Saleski; Jian-He Xu; Peter Meinhold; Frances H Arnold
Journal:  J Biotechnol       Date:  2012-09-03       Impact factor: 3.307

5.  Furfural reduction mechanism of a zinc-dependent alcohol dehydrogenase from Cupriavidus necator JMP134.

Authors:  ChulHee Kang; Robert Hayes; Emiliano J Sanchez; Brian N Webb; Qunrui Li; Travis Hooper; Mark S Nissen; Luying Xun
Journal:  Mol Microbiol       Date:  2011-11-20       Impact factor: 3.501

6.  Identification and characterization of 2-keto-3-deoxy-L-rhamnonate dehydrogenase belonging to the MDR superfamily from the thermoacidophilic bacterium Sulfobacillus thermosulfidooxidans: implications to L-rhamnose metabolism in archaea.

Authors:  Jungdon Bae; Suk Min Kim; Sun Bok Lee
Journal:  Extremophiles       Date:  2015-01-24       Impact factor: 2.395

7.  Crystallization and preliminary X-ray diffraction analysis of (R)-carbonyl reductase from Candida parapsilosis.

Authors:  Shanshan Wang; Yao Nie; Xu Yan; Tzu-Ping Ko; Chun-Hsiang Huang; Hsiu-Chien Chan; Rey-Ting Guo; Rong Xiao
Journal:  Acta Crystallogr F Struct Biol Commun       Date:  2014-05-24       Impact factor: 1.056

8.  Role of tryptophan 95 in substrate specificity and structural stability of Sulfolobus solfataricus alcohol dehydrogenase.

Authors:  Angela Pennacchio; Luciana Esposito; Adriana Zagari; Mosè Rossi; Carlo A Raia
Journal:  Extremophiles       Date:  2009-07-09       Impact factor: 2.395

Review 9.  Conformational changes and catalysis by alcohol dehydrogenase.

Authors:  Bryce V Plapp
Journal:  Arch Biochem Biophys       Date:  2009-07-05       Impact factor: 4.013

10.  Effects of cavities at the nicotinamide binding site of liver alcohol dehydrogenase on structure, dynamics and catalysis.

Authors:  Atsushi Yahashiri; Jon K Rubach; Bryce V Plapp
Journal:  Biochemistry       Date:  2014-01-30       Impact factor: 3.162

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