Literature DB >> 19009924

[Evaluation of the efficacy of the Toxoplasma gondii screening program among pregnant women in Nunavik, 1994-2003].

Elaine Lavoie1, Benoit Lévesque, Jean-François Proulx, Jennifer Grant, Angéla Davys Ndassebe, Suzanne Gingras, Bruno Hubert, Michael Libman.   

Abstract

OBJECTIVES: (1) To evaluate the efficacy of the Toxoplasma gondii screening program among Nunavik pregnant women in identifying seroconversions during pregnancy and performing an appropriate follow-up of the seroconverted women and their child; and (2) to evaluate the consequences of congenital Toxoplasma gondii infection. PARTICIPANTS: Women of child-bearing age and their children born between January 1994 and September 2003.
SETTING: Nunavik. INTERVENTION: Potential cases of infection during pregnancy and of congenital toxoplasmosis were identified on the basis of serologic and hospitalization data. A medical chart revision was then performed. Descriptive statistics regarding the medical follow-up and treatment of suspected cases were compiled. OUTCOMES: 31 women who gave birth to 32 children were identified as potential cases. According to the medical charts, 19 women had a potential infection during pregnancy, the others were deemed to have been infected before conception. One woman had a definite infection. This woman and most of the 18 other potentially infected women and their children were treated appropriately. Because of missing data, it was impossible to determine with certainty the final status of two children. A diagnosis of congenital infection was rejected among the other children.
CONCLUSION: Women with suspected infection and their children were generally well managed by the health care system. No clinical effect of congenital toxoplasmosis was noted during the studied period.

Entities:  

Mesh:

Year:  2008        PMID: 19009924      PMCID: PMC6976170     

Source DB:  PubMed          Journal:  Can J Public Health        ISSN: 0008-4263


  7 in total

Review 1.  Effectiveness of prenatal treatment for congenital toxoplasmosis: a meta-analysis of individual patients' data.

Authors:  Rodolphe Thiébaut; Sandy Leproust; Geneviève Chêne; Ruth Gilbert
Journal:  Lancet       Date:  2007-01-13       Impact factor: 79.321

2.  An outbreak of toxoplasmosis in pregnant women in northern Québec.

Authors:  J C McDonald; T W Gyorkos; B Alberton; J D MacLean; G Richer; D Juranek
Journal:  J Infect Dis       Date:  1990-04       Impact factor: 5.226

3.  Mother-to-child transmission of toxoplasmosis: risk estimates for clinical counselling.

Authors:  D Dunn; M Wallon; F Peyron; E Petersen; C Peckham; R Gilbert
Journal:  Lancet       Date:  1999-05-29       Impact factor: 79.321

4.  Congenital toxoplasmosis: systematic review of evidence of efficacy of treatment in pregnancy.

Authors:  M Wallon; C Liou; P Garner; F Peyron
Journal:  BMJ       Date:  1999-06-05

Review 5.  Treatments for toxoplasmosis in pregnancy.

Authors:  F Peyron; M Wallon; C Liou; P Garner
Journal:  Cochrane Database Syst Rev       Date:  2000

Review 6.  Preventing congenital toxoplasmosis.

Authors:  A Lopez; V J Dietz; M Wilson; T R Navin; J L Jones
Journal:  MMWR Recomm Rep       Date:  2000-03-31

7.  Long-term ocular prognosis in 327 children with congenital toxoplasmosis.

Authors:  Martine Wallon; Laurent Kodjikian; Christine Binquet; Justus Garweg; Jacques Fleury; Catherine Quantin; François Peyron
Journal:  Pediatrics       Date:  2004-06       Impact factor: 7.124

  7 in total
  4 in total

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Authors:  Joseph P Dudley; Eric P Hoberg; Emily J Jenkins; Alan J Parkinson
Journal:  Ecohealth       Date:  2015-06-13       Impact factor: 3.184

2.  Toxoplasmosis and Toxocariasis: An Assessment of Human Immunodeficiency Virus Comorbidity and Health-Care Costs in Canada.

Authors:  Janna M Schurer; Ellen Rafferty; Michael Schwandt; Wu Zeng; Marwa Farag; Emily J Jenkins
Journal:  Am J Trop Med Hyg       Date:  2016-05-02       Impact factor: 2.345

3.  The burgeoning field of transdisciplinary adaptation research in Quebec (1998-): a climate change-related public health narrative.

Authors:  Pierre Gosselin; Diane Bélanger; Véronique Lapaige; Yolaine Labbé
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4.  Foxes (Vulpes vulpes) as sentinels for parasitic zoonoses, Toxoplasma gondii and Trichinella nativa, in the northeastern Canadian Arctic.

Authors:  Bachand Nicholas; A Ravel; P Leighton; C Stephen; A Iqbal; M Ndao; K Konecsni; C Fernando; E Jenkins
Journal:  Int J Parasitol Parasites Wildl       Date:  2018-10-17       Impact factor: 2.674

  4 in total

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