Literature DB >> 19008474

Variation in outcome after subarachnoid hemorrhage: a study of neurosurgical units in UK and Ireland.

Julia Langham1, Barnaby C Reeves, Kenneth W Lindsay, Jan H van der Meulen, Peter J Kirkpatrick, Anil R Gholkar, Andrew J Molyneux, Donald M Shaw, Lynn Copley, John P Browne.   

Abstract

BACKGROUNDS AND
PURPOSE: The purpose of the study was to describe the characteristics, management, and outcomes of patients with confirmed aneurysmal subarachnoid hemorrhage and to compare outcomes across neurosurgical units (NSUs) in the UK and Ireland.
METHODS: A cohort of patients admitted to NSUs with subarachnoid hemorrhage between September 14, 2001 and September 13, 2002 was studied longitudinally. Information was collected to characterize clinical condition on admission and treatment. Death or severe disability, defined by the Glasgow Outcome Score-Extended, was ascertained at 6 months.
RESULTS: Data for 2397 patients with a confirmed aneurysm and no coexisting neurological pathology were collected by all 34 NSUs in the UK and Ireland. Aneurysm repair was attempted in 2198 (91.7%) patients (surgical clipping, 57.7%; endovascular coiling, 41.2%; other repair, 1.0%). Most patients (65.0%) were admitted to the NSU on the same day or the day after their hemorrhage; 32.0% of treated patients had the aneurysm repaired on the day of admission to the NSU (day 0), day 1 or day 2 and a further 39.3% by day 7. Glasgow Outcome Score-Extended at 6 months was obtained for 90.6% of patients (2172), of whom 38.5% had an unfavorable outcome. The median risk of an unfavorable outcome for all patients was 31% (5(th) and 95(th) percentiles, 12% and 83%), depending on prerepair prognostic factors. After adjustment for case-mix, the percentage of patients with an unfavorable outcome in each NSU did not differ significantly from the overall mean.
CONCLUSIONS: In this study that collected representative data from the UK and Ireland, there was no evidence that the performance of any NSU differed from the average.

Entities:  

Mesh:

Year:  2008        PMID: 19008474     DOI: 10.1161/STROKEAHA.108.517805

Source DB:  PubMed          Journal:  Stroke        ISSN: 0039-2499            Impact factor:   7.914


  14 in total

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Authors:  R Risselada; H F Lingsma; A Bauer-Mehren; C M Friedrich; A J Molyneux; R S C Kerr; J Yarnold; M Sneade; E W Steyerberg; M C J M Sturkenboom
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Review 2.  High-volume centers.

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Authors:  Abdel-Hameed Al-Mistarehi; Muaz A Elsayed; Rihab M Ibrahim; Tarig Hassan Elzubair; Safaa Badi; Mohamed H Ahmed; Raed Alkhaddash; Musaab K Ali; Yousef S Khader; Safwan Alomari
Journal:  Neurohospitalist       Date:  2022-02-18

4.  Regional Variability in the Care and Outcomes of Subarachnoid Hemorrhage Patients in the United States.

Authors:  Vishank A Shah; Syed Omar Kazmi; Rahul Damani; Alyssa Hartsell Harris; Samuel F Hohmann; Eusebia Calvillo; Jose I Suarez
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5.  Prediction of two month modified Rankin Scale with an ordinal prediction model in patients with aneurysmal subarachnoid haemorrhage.

Authors:  Roelof Risselada; Hester F Lingsma; Andrew J Molyneux; Richard S C Kerr; Julia Yarnold; Mary Sneade; Ewout W Steyerberg; Miriam C J M Sturkenboom
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Review 6.  Lessons Learned from Phase II and Phase III Trials Investigating Therapeutic Agents for Cerebral Ischemia Associated with Aneurysmal Subarachnoid Hemorrhage.

Authors:  Adnan I Qureshi; Iryna Lobanova; Wei Huang; Muhammad F Ishfaq; Joseph P Broderick; Christy N Cassarly; Renee H Martin; R Loch Macdonald; Jose I Suarez
Journal:  Neurocrit Care       Date:  2021-12-23       Impact factor: 3.210

7.  The durability of endovascular coiling versus neurosurgical clipping of ruptured cerebral aneurysms: 18 year follow-up of the UK cohort of the International Subarachnoid Aneurysm Trial (ISAT).

Authors:  Andrew J Molyneux; Jacqueline Birks; Alison Clarke; Mary Sneade; Richard S C Kerr
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Authors:  Barnaby C Reeves; George A Wells; Hugh Waddington
Journal:  J Clin Epidemiol       Date:  2017-03-27       Impact factor: 6.437

Review 9.  Applicability and generalisability of published results of randomised controlled trials and non-randomised studies evaluating four orthopaedic procedures: methodological systematic review.

Authors:  Leslie Pibouleau; Isabelle Boutron; Barnaby C Reeves; Rémy Nizard; Philippe Ravaud
Journal:  BMJ       Date:  2009-11-17

10.  The clinical profile, management, and overall outcome of aneurysmal subarachnoid hemorrhage at the neurosurgical unit of a tertiary care center in India.

Authors:  Harsimrat Bir Singh Sodhi; Amey R Savardekar; Sandeep Mohindra; Rajesh Chhabra; Vivek Gupta; Sunil K Gupta
Journal:  J Neurosci Rural Pract       Date:  2014-04
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