Literature DB >> 19005242

Open-ended question: is immortality exclusively inherent to the germline?--A mini-review.

Günter Lepperdinger1.   

Abstract

All somatic cells are subject to aging. Germline links generations, and thus, pluripotent germ cells are considered potentially immortal. The current understanding how the germline escapes this otherwise inevitable phenomenon is outlined in this article. (c) 2008 S. Karger AG, Basel.

Mesh：

Year:  2008        PMID： 19005242     DOI： 10.1159/000173977

Source DB:  PubMed          Journal:  Gerontology        ISSN： 0304-324X            Impact factor:   5.140


  6 in total

1.  Old age as a privilege of the "selfish ones".

Authors:  Mladen Davidovic; Goran Sevo; Petar Svorcan; Dragoslav P Milosevic; Nebojsa Despotovic; Predrag Erceg
Journal:  Aging Dis       Date:  2010-07-30       Impact factor: 6.745

2.  Reevaluation of whether a soma-to-germ-line transformation extends lifespan in Caenorhabditis elegans.

Authors:  Andrew Kekūpa'a Knutson; Andreas Rechtsteiner; Susan Strome
Journal:  Proc Natl Acad Sci U S A       Date:  2016-03-14       Impact factor: 11.205

Review 3.  The Ground Zero of Organismal Life and Aging.

Authors:  Vadim N Gladyshev
Journal:  Trends Mol Med       Date:  2020-09-23       Impact factor: 15.272

Review 4.  Age-associated changes in the ecological niche: implications for mesenchymal stem cell aging.

Authors:  Faizal Z Asumda
Journal:  Stem Cell Res Ther       Date:  2013-05-14       Impact factor: 6.832

5.  Karyotype alteration generates the neoplastic phenotypes of SV40-infected human and rodent cells.

Authors:  Mathew Bloomfield; Peter Duesberg
Journal:  Mol Cytogenet       Date:  2015-10-22       Impact factor: 2.009

6.  Epigenetic clocks reveal a rejuvenation event during embryogenesis followed by aging.

Authors:  Csaba Kerepesi; Bohan Zhang; Sang-Goo Lee; Alexandre Trapp; Vadim N Gladyshev
Journal:  Sci Adv       Date:  2021-06-25       Impact factor: 14.136
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.