Literature DB >> 19003613

Four new biflavonoids from Selaginella uncinata and their anti-anoxic effect.

Jun-Xia Zheng1, Nai-Li Wang, Hong-Wei Liu, Hai-Feng Chen, Ming-Ming Li, Li-Ying Wu, Ming Fan, Xin-Sheng Yao.   

Abstract

The 60% ethanolic extract of Selaginella uncinata (Desv.) Spring possessed potent anti-anoxic effect in the anoxic PC12 cell assay. A phytochemical study of its EtOAc-soluble part led to the isolation of four new and three known biflavonoids. Their structures were established on the basis of physico-chemical properties and spectroscopic analysis. The absolute configurations of the new compounds were determined with the aid of circular dichroism (CD) spectroscopy. Compounds 4 and 5 showed potent anti-anoxic effect in the anoxic PC12 cell assay.

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Year:  2008        PMID: 19003613     DOI: 10.1080/10286020802181166

Source DB:  PubMed          Journal:  J Asian Nat Prod Res        ISSN: 1028-6020            Impact factor:   1.569


  7 in total

1.  Neuroprotective effect of aqueous extract of Selaginella delicatula as evidenced by abrogation of rotenone-induced motor deficits, oxidative dysfunctions, and neurotoxicity in mice.

Authors:  Girish Chandran
Journal:  Cell Mol Neurobiol       Date:  2013-07-19       Impact factor: 5.046

2.  Flavonoids from Selaginella doederleinii Hieron and Their Antioxidant and Antiproliferative Activities.

Authors:  Felix Wambua Muema; Ye Liu; Yongli Zhang; Guilin Chen; Mingquan Guo
Journal:  Antioxidants (Basel)       Date:  2022-06-17

3.  New 3',8''-linked biflavonoids from Selaginella uncinata displaying protective effect against anoxia.

Authors:  Jun-Xia Zheng; Yang Zheng; Hui Zhi; Yi Dai; Nai-Li Wang; Yan-Xiong Fang; Zhi-Yun Du; Kun Zhang; Ming-Ming Li; Li-Ying Wu; Ming Fan
Journal:  Molecules       Date:  2011-07-25       Impact factor: 4.411

4.  Anatomical and Biochemical Traits Related to Blue Leaf Coloration of Selaginella uncinata.

Authors:  Lin Li; Lulu Yang; Aihua Qin; Fangyi Jiang; Limei Chen; Rongyan Deng
Journal:  J Healthc Eng       Date:  2022-02-24       Impact factor: 2.682

5.  Chemodiversity in Selaginella: a reference system for parallel and convergent metabolic evolution in terrestrial plants.

Authors:  Jing-Ke Weng; Joseph P Noel
Journal:  Front Plant Sci       Date:  2013-05-10       Impact factor: 5.753

6.  Amentoflavone ameliorates cold stress-induced inflammation in lung by suppression of C3/BCR/NF-κB pathways.

Authors:  Jiayi Cai; Chunyang Zhao; Yajie Du; Yuan Huang; Qingchun Zhao
Journal:  BMC Immunol       Date:  2019-12-30       Impact factor: 3.615

7.  Biflavonoids from Selaginella doederleinii as Potential Antitumor Agents for Intervention of Non-Small Cell Lung Cancer.

Authors:  Fenghua Kang; Sha Zhang; Dekun Chen; Jianbing Tan; Min Kuang; Jinlin Zhang; Guangyuan Zeng; Kangping Xu; Zhenxing Zou; Guishan Tan
Journal:  Molecules       Date:  2021-09-05       Impact factor: 4.411

  7 in total

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