Literature DB >> 1900159

Assessment of the drug inhibitor specificity of the human liver 4-methylumbelliferone UDP-glucuronosyltransferase activity.

J O Miners1, K J Lillywhite.   

Abstract

The data suggest that the 4MU-UDPGT activity of human liver microsomes probably contributes to the glucuronidation of a limited number of clinically used drugs. However, confirmation of this ultimately requires studies to be performed with purified isozymes, cDNAs expressed in cell culture, or specific inhibitory antibodies.

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Year:  1991        PMID： 1900159     DOI： 10.1016/0006-2952(91)90090-r

Source DB:  PubMed          Journal:  Biochem Pharmacol        ISSN： 0006-2952            Impact factor:   5.858


  4 in total

1.  Cloning and stable expression of a new member of the human liver phenol/bilirubin: UDP-glucuronosyltransferase cDNA family.

Authors:  R Wooster; L Sutherland; T Ebner; D Clarke; O Da Cruz e Silva; B Burchell
Journal:  Biochem J       Date:  1991-09-01       Impact factor: 3.857

2.  Extrahepatic metabolism of zidovudine.

Authors:  J L Howe; D J Back; J Colbert
Journal:  Br J Clin Pharmacol       Date:  1992-02       Impact factor: 4.335

Review 3.  UDP-glucuronosyltransferase inhibitors.

Authors:  E Golovinsky; Z Naydenova; K Grancharov
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1998 Oct-Dec       Impact factor: 2.569

Review 4.  Interaction of carbamazepine with herbs, dietary supplements, and food: a systematic review.

Authors:  Sophia Yui Kau Fong; Qiong Gao; Zhong Zuo
Journal:  Evid Based Complement Alternat Med       Date:  2013-08-19       Impact factor: 2.629
  4 in total

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