| Literature DB >> 18996570 |
Debasis Chakrabarty1, Prabodh Kumar Trivedi, Prashant Misra, Manish Tiwari, Manju Shri, Devesh Shukla, Smita Kumar, Arti Rai, Ashutosh Pandey, Deepti Nigam, Rudra Dev Tripathi, Rakesh Tuli.
Abstract
The effect of arsenic (As) exposure on genome-wide expression was examined in rice (Oryza sativa L., ssp. Indica). A group of defense and stress-responsive genes, transporters, heat-shock proteins, metallothioneins, sulfate-metabolizing proteins, and regulatory genes showed differential expression in rice seedlings challenged with arsenate (AsV) and arsenite (AsIII). AsV stress led to upregulation or downregulation of an additional set of genes in comparison to AsIII. Differential expression of several genes that showed the highest contrast in a microarray analysis was validated by following the quantitative changes in the levels of individual transcripts following challenge with AsV, AsIII, Cd, Cr, and Pb. Most of the selected genes responded to challenge by heavy metals such as arsenic. However, expression of one of the cytochrome P450 genes (Os01g43740) in rice root was induced by AsV but not by other heavy metals. Similarly, one glutaredoxin (Os01g26912) is expressed specifically in the AsIII-treated shoot.Entities:
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Year: 2008 PMID： 18996570 DOI： 10.1016/j.chemosphere.2008.09.082
Source DB: PubMed Journal: Chemosphere ISSN： 0045-6535 Impact factor: 7.086