| Literature DB >> 18992956 |
Mireya Plass1, Eneritz Agirre, Diana Reyes, Francisco Camara, Eduardo Eyras.
Abstract
Serine-arginine-rich (SR) proteins are essential for splicing in metazoans but are absent in yeast. By contrast, many fungi have SR protein homologs with variable arginine-rich regions analogous to the arginine-serine-rich (RS) domain in metazoans. The density of RS repeats in these regions correlates with the conservation of the branch site signal, providing evidence for an ancestral origin of SR proteins and indicating that the SR proteins and the branch site co-evolved.Entities:
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Year: 2008 PMID： 18992956 DOI： 10.1016/j.tig.2008.10.004
Source DB: PubMed Journal: Trends Genet ISSN： 0168-9525 Impact factor: 11.639