Literature DB >> 18990581

Production of the Auger emitter 119Sb for targeted radionuclide therapy using a small PET-cyclotron.

H Thisgaard1, M Jensen.   

Abstract

The use of Auger electrons in radionuclide therapy of cancer is a promising tool for specific tumor cell killing of micrometastases and small tumors. The radioisotope (119)Sb has recently been identified as a potent Auger-emitter for therapy. We here present a method for producing this isotope using a low-energy cyclotron. With this method, it will be possible to produce clinically relevant amounts of (119)Sb radioactivity with high chemical and radionuclidic purity for cancer therapy.

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Year:  2008        PMID： 18990581     DOI： 10.1016/j.apradiso.2008.09.003

Source DB:  PubMed          Journal:  Appl Radiat Isot        ISSN： 0969-8043            Impact factor:   1.513


  3 in total

1.  Meitner-Auger Electron Emitters for Targeted Radionuclide Therapy: Mercury-197m/g and Antimony-119

Authors:  Parmissa Randhawa; Aeli P Olson; Shaohuang Chen; Kaley Lexi Gower-Fry; Cornelia Hoehr; Jonathan W Engle; Caterina F Ramogida; Valery Radchenko
Journal:  Curr Radiopharm       Date:  2021

2.  A Third Generation Potentially Bifunctional Trithiol Chelate, Its nat,1XXSb(III) Complex, and Selective Chelation of Radioantimony (119Sb) from Its Sn Target.

Authors:  Aeli P Olson; Li Ma; Yutian Feng; Firouzeh Najafi Khosroshahi; Steven P Kelley; Eduardo Aluicio-Sarduy; Todd E Barnhart; Heather M Hennkens; Paul A Ellison; Silvia S Jurisson; Jonathan W Engle
Journal:  Inorg Chem       Date:  2021-10-04       Impact factor: 5.165

3.  The Paradox of Using Radionuclides To Treat Disease.

Authors:  Thomas E Albrecht-Schmitt
Journal:  ACS Cent Sci       Date:  2019-02-25       Impact factor: 14.553
  3 in total

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