Literature DB >> 189905

Enhancement of diethylnitrosamine hepatocarcinogenesis in rats by exposure to polychlorinated biphenyls or phenobarbital.

M Nishizumi.   

Abstract

Diethylnitrosamine (DENA) hepatocarcinogenesis was enhanced by sequential exposure with polychlorinated biphenyls (PCBs) and with phenobarbital. This was shown by the earlier appearance of tumors and a significant increase in the number of tumors. However, there was no evidence suggesting an acceleration of tumor growth.

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Year:  1976        PMID： 189905     DOI： 10.1016/s0304-3835(76)80004-3

Source DB:  PubMed          Journal:  Cancer Lett        ISSN： 0304-3835            Impact factor:   8.679


  10 in total

1.  Nuclear receptors CAR and PXR in the regulation of hepatic metabolism.

Authors:  E S Tien; M Negishi
Journal:  Xenobiotica       Date:  2006 Oct-Nov       Impact factor: 1.908

Review 2.  Small-molecule modulators of the constitutive androstane receptor.

Authors:  Milu T Cherian; Sergio C Chai; Taosheng Chen
Journal:  Expert Opin Drug Metab Toxicol       Date:  2015-05-15       Impact factor: 4.481

3.  Effect of phenobarbital on the development of neoplastic lesions in the liver of cycasin-treated rats.

Authors:  E Uchida; I Hirono
Journal:  J Cancer Res Clin Oncol       Date:  1981       Impact factor: 4.553

4.  Assessment of oxidative metabolism in adults with hepatocellular carcinoma in the Sudan.

Authors:  M M Homeida; T K Daneshmend; E M Ali; A G Yousif-Elkadaru; B M Arbab
Journal:  Gut       Date:  1986-04       Impact factor: 23.059

5.  Promoting effect of polychlorinated biphenyls on development of enzyme-altered islands in livers of weanling and adult rats.

Authors:  D Oesterle; E Deml
Journal:  J Cancer Res Clin Oncol       Date:  1983       Impact factor: 4.553

6.  Comparative evaluation of genetic toxicity patterns of carcinogens and noncarcinogens: strategies for predictive use of short-term assays.

Authors:  R W Tennant; J W Spalding; S Stasiewicz; W D Caspary; J M Mason; M A Resnick
Journal:  Environ Health Perspect       Date:  1987-11       Impact factor: 9.031

Review 7.  Carcinogenicity of by-products of disinfection in mouse and rat liver.

Authors:  S L Herren-Freund; M A Pereira
Journal:  Environ Health Perspect       Date:  1986-11       Impact factor: 9.031

8.  Distinctive biochemical pattern associated with resistance of hepatocytes in hepatocyte nodules during liver carcinogenesis.

Authors:  L Eriksson; M Ahluwalia; J Spiewak; G Lee; D S Sarma; M J Roomi; E Farber
Journal:  Environ Health Perspect       Date:  1983-03       Impact factor: 9.031

9.  Tumor promotion in rat liver.

Authors:  S L Herren; M A Pereira
Journal:  Environ Health Perspect       Date:  1983-04       Impact factor: 9.031

10.  Proliferative lesions of the glandular stomach and liver in F344 rats fed diets containing Aroclor 1254.

Authors:  J M Ward
Journal:  Environ Health Perspect       Date:  1985-05       Impact factor: 9.031
  10 in total

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