Literature DB >> 18990415

Low-cost interventions accelerate epidemiological transition in Upper East Ghana.

J J Meij1, A J M de Craen, J Agana, D Plug, R G J Westendorp.   

Abstract

Before the 1950s effective medical interventions were not available and epidemiological transition in developing countries was mostly initiated by the introduction of mains water, sewage systems and personal hygiene. Nowadays, effective medical interventions such as vaccination programmes, medication and vitamin supplements might aid a swift transition. We recorded mortality among a research population of 18850 in Garu-Tempane district of Ghana from 2002 to 2005. We calculated the expected mortality based on the population structure in 2002 and compared the life expectancy of the region with other countries depending on their gross domestic product (GDP). Mortality in the age group 0-9 years was 8.1 per 1000 person-years and in the age group 10-19 years it was 4.1 per 1000 person-years. Cumulative survival probability up to age 20 years amounted to 89% and was far higher than expected. Observed and expected mortality in old age were similar. The life expectancy at birth was 59 years and much higher than the region's per capita annual income of US$100 would predict. We conclude that the population is in epidemiological transition. It shows that an epidemiological transition can be accelerated with low-cost interventions.

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Year:  2008        PMID: 18990415     DOI: 10.1016/j.trstmh.2008.09.015

Source DB:  PubMed          Journal:  Trans R Soc Trop Med Hyg        ISSN: 0035-9203            Impact factor:   2.184


  9 in total

1.  Polymorphisms in TLR4 and TLR2 genes, cytokine production and survival in rural Ghana.

Authors:  Linda May; David van Bodegom; Marijke Frölich; Lisette van Lieshout; P Eline Slagboom; Rudi G J Westendorp; Maris Kuningas
Journal:  Eur J Hum Genet       Date:  2009-10-21       Impact factor: 4.246

2.  Socioeconomic status determines sex-dependent survival of human offspring.

Authors:  David van Bodegom; Maarten P Rozing; Linda May; Hans J Meij; Fleur Thomése; Bas J Zwaan; Rudi G J Westendorp
Journal:  Evol Med Public Health       Date:  2013-03-01

3.  Genetic variants determining survival and fertility in an adverse African environment: a population-based large-scale candidate gene association study.

Authors:  Jacob J E Koopman; Jeroen Pijpe; Stefan Böhringer; David van Bodegom; Ulrika K Eriksson; Hernando Sanchez-Faddeev; Juventus B Ziem; Bas Zwaan; P Eline Slagboom; Peter de Knijff; Rudi G J Westendorp
Journal:  Aging (Albany NY)       Date:  2016-07       Impact factor: 5.682

4.  Mortality and risk factors of disease in Nepal: Trend and projections from 1990 to 2040.

Authors:  Achyut Raj Pandey; Binaya Chalise; Niraj Shrestha; Biwesh Ojha; Jasmine Maskey; Dikshya Sharma; Peter Godwin; Krishna Kumar Aryal
Journal:  PLoS One       Date:  2020-12-03       Impact factor: 3.240

5.  Selection for genetic variation inducing pro-inflammatory responses under adverse environmental conditions in a Ghanaian population.

Authors:  Maris Kuningas; Linda May; Riin Tamm; David van Bodegom; Anita H J van den Biggelaar; Johannes J Meij; Marijke Frölich; Juventus B Ziem; Helena E D Suchiman; Andres Metspalu; P Eline Slagboom; Rudi G J Westendorp
Journal:  PLoS One       Date:  2009-11-11       Impact factor: 3.240

6.  Common CFTR gene variants influence body composition and survival in rural Ghana.

Authors:  Maris Kuningas; David van Bodegom; Linda May; Johannes J Meij; P Eline Slagboom; Rudi G J Westendorp
Journal:  Hum Genet       Date:  2009-11-05       Impact factor: 4.132

7.  Risk of cardiovascular disease in a traditional African population with a high infectious load: a population-based study.

Authors:  Jacob J E Koopman; David van Bodegom; J Wouter Jukema; Rudi G J Westendorp
Journal:  PLoS One       Date:  2012-10-11       Impact factor: 3.240

8.  Adverse environmental conditions influence age-related innate immune responsiveness.

Authors:  Linda May; Anita H J van den Biggelaar; David van Bodegom; Hans J Meij; Anton J M de Craen; Joseph Amankwa; Marijke Frölich; Maris Kuningas; Rudi G J Westendorp
Journal:  Immun Ageing       Date:  2009-05-30       Impact factor: 6.400

9.  Scarcity of atrial fibrillation in a traditional African population: a community-based study.

Authors:  Jacob J E Koopman; David van Bodegom; Rudi G J Westendorp; Johan Wouter Jukema
Journal:  BMC Cardiovasc Disord       Date:  2014-07-18       Impact factor: 2.298

  9 in total

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