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Literature DB >> 18987987

The biochemistry, metabolism and inherited defects of the pentose phosphate pathway: a review.

Abstract

The recent discovery of two defects (ribose-5-phosphate isomerase deficiency and transaldolase deficiency) in the reversible part of the pentose phosphate pathway (PPP) has stimulated interest in this pathway. In this review we describe the functions of the PPP, its relation to other pathways of carbohydrate metabolism and an overview of the metabolic defects in the reversible part of the PPP.

Entities: Chemical Disease Gene

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Year: 2008 PMID： 18987987 DOI： 10.1007/s10545-008-1015-6

Source DB: PubMed Journal: J Inherit Metab Dis ISSN： 0141-8955 Impact factor: 4.982

56 in total

1. Quantification of sugar phosphate intermediates of the pentose phosphate pathway by LC-MS/MS: application to two new inherited defects of metabolism.

Authors: Mirjam M C Wamelink; Eduard A Struys; Jojanneke H J Huck; Birthe Roos; Marjo S van der Knaap; Cornelis Jakobs; Nanda M Verhoeven
Journal: J Chromatogr B Analyt Technol Biomed Life Sci Date: 2005-01-23 Impact factor: 3.205

2. A newborn with severe liver failure, cardiomyopathy and transaldolase deficiency.

Authors: N M Verhoeven; M Wallot; J H J Huck; O Dirsch; A Ballauf; U Neudorf; G S Salomons; M S van der Knaap; T Voit; C Jakobs
Journal: J Inherit Metab Dis Date: 2005 Impact factor: 4.982

3. Glutathione levels and sensitivity to apoptosis are regulated by changes in transaldolase expression.

Authors: K Banki; E Hutter; E Colombo; N J Gonchoroff; A Perl
Journal: J Biol Chem Date: 1996-12-20 Impact factor: 5.157

4. Profiling of pentose phosphate pathway intermediates in blood spots by tandem mass spectrometry: application to transaldolase deficiency.

Authors: Jojanneke H J Huck; Eduard A Struys; Nanda M Verhoeven; Cornelis Jakobs; Marjo S van der Knaap
Journal: Clin Chem Date: 2003-08 Impact factor: 8.327

5. Improved method of analysis of biomass sugars using high-performance liquid chromatography.

Authors: F A Agblevor; A Murden; B R Hames
Journal: Biotechnol Lett Date: 2004-08 Impact factor: 2.461

6. Transaldolase deficiency influences the pentose phosphate pathway, mitochondrial homoeostasis and apoptosis signal processing.

Authors: Yueming Qian; Sanjay Banerjee; Craig E Grossman; Wendy Amidon; Gyorgy Nagy; Maureen Barcza; Brian Niland; David R Karp; Frank A Middleton; Katalin Banki; Andras Perl
Journal: Biochem J Date: 2008-10-01 Impact factor: 3.857

7. High-performance liquid chromatographic system for separating sugar phosphates and other intermediary metabolites.

Authors: R R Swezey
Journal: J Chromatogr B Biomed Appl Date: 1995-07-21

8. Potential role of nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase in apoptosis and oxidative stress.

Authors: Z Dastoor; J L Dreyer
Journal: J Cell Sci Date: 2001-05 Impact factor: 5.285

9. Expression of transketolase TKTL1 predicts colon and urothelial cancer patient survival: Warburg effect reinterpreted.

Authors: S Langbein; M Zerilli; A Zur Hausen; W Staiger; K Rensch-Boschert; N Lukan; J Popa; M P Ternullo; A Steidler; C Weiss; R Grobholz; F Willeke; P Alken; G Stassi; P Schubert; J F Coy
Journal: Br J Cancer Date: 2006-02-27 Impact factor: 7.640

10. Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress.

Authors: Markus Ralser; Mirjam M Wamelink; Axel Kowald; Birgit Gerisch; Gino Heeren; Eduard A Struys; Edda Klipp; Cornelis Jakobs; Michael Breitenbach; Hans Lehrach; Sylvia Krobitsch
Journal: J Biol Date: 2007-12-21

107 in total

1. Reduced neuronal expression of ribose-5-phosphate isomerase enhances tolerance to oxidative stress, extends lifespan, and attenuates polyglutamine toxicity in Drosophila.

Authors: Ching-Tzu Wang; Yi-Chun Chen; Yi-Yun Wang; Ming-Hao Huang; Tzu-Li Yen; Hsun Li; Cyong-Jhih Liang; Tzu-Kang Sang; Shih-Ci Ciou; Chiou-Hwa Yuh; Chao-Yung Wang; Theodore J Brummel; Horng-Dar Wang
Journal: Aging Cell Date: 2011-11-28 Impact factor: 9.304

Review 2. The redox basis of epigenetic modifications: from mechanisms to functional consequences.

Authors: Anthony R Cyr; Frederick E Domann
Journal: Antioxid Redox Signal Date: 2011-02-05 Impact factor: 8.401

3. The unexplored potential of the pentose phosphate pathway in health and disease.

Authors: Gerard T Berry
Journal: J Inherit Metab Dis Date: 2008-12 Impact factor: 4.982

4. Metabolic profiling reveals biochemical pathways and potential biomarkers associated with the pathogenesis of Krabbe disease.

Authors: Nadav I Weinstock; Lawrence Wrabetz; M Laura Feltri; Daesung Shin
Journal: J Neurosci Res Date: 2016-11 Impact factor: 4.164

5. Metabolic reconfiguration precedes transcriptional regulation in the antioxidant response.

Authors: Markus Ralser; Mirjam M C Wamelink; Simone Latkolik; Erwin E W Jansen; Hans Lehrach; Cornelis Jakobs
Journal: Nat Biotechnol Date: 2009-07 Impact factor: 54.908

6. Prevention of hepatocellular adenoma and correction of metabolic abnormalities in murine glycogen storage disease type Ia by gene therapy.

Authors: Young Mok Lee; Hyun Sik Jun; Chi-Jiunn Pan; Su Ru Lin; Lane H Wilson; Brian C Mansfield; Janice Y Chou
Journal: Hepatology Date: 2012-08-27 Impact factor: 17.425