Literature DB >> 18987660

Heterozygosity at the TPMT gene locus, augmented by mutated MTHFR gene, predisposes to 6-MP related toxicities in childhood ALL patients.

N Karas-Kuzelicki, J Jazbec, M Milek, I Mlinaric-Rascan.   

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Year:  2008        PMID: 18987660     DOI: 10.1038/leu.2008.317

Source DB:  PubMed          Journal:  Leukemia        ISSN: 0887-6924            Impact factor:   11.528


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  21 in total

1.  Precision therapy of 6-mercaptopurine in Chinese children with acute lymphoblastic leukaemia.

Authors:  Yue Zhou; Li Wang; Xiao-Ying Zhai; Li Wen; Fang Tang; Fan Yang; Xi-Ting Liu; Lei Dong; Li-Juan Zhi; Hai-Yan Shi; Guo-Xiang Hao; Yi Zheng; Evelyne Jacqz-Aigrain; Tian-You Wang; Wei Zhao
Journal:  Br J Clin Pharmacol       Date:  2020-03-03       Impact factor: 4.335

Review 2.  Pharmacogenetic Predictors of Treatment-Related Toxicity Among Children With Acute Lymphoblastic Leukemia.

Authors:  Rochelle R Maxwell; Peter D Cole
Journal:  Curr Hematol Malig Rep       Date:  2017-06       Impact factor: 3.952

Review 3.  Pharmacogenetic determinants of mercaptopurine disposition in children with acute lymphoblastic leukemia.

Authors:  Tiphaine Adam de Beaumais; Evelyne Jacqz-Aigrain
Journal:  Eur J Clin Pharmacol       Date:  2012-03-16       Impact factor: 2.953

4.  Multidrug resistance protein 4 (MRP4) polymorphisms impact the 6-mercaptopurine dose tolerance during maintenance therapy in Japanese childhood acute lymphoblastic leukemia.

Authors:  Y Tanaka; A Manabe; H Fukushima; R Suzuki; H Nakadate; K Kondoh; K Nakamura; K Koh; T Fukushima; M Tsuchida; K Koike; N Kiyokawa; E Noguchi; R Sumazaki; T Komiyama
Journal:  Pharmacogenomics J       Date:  2014-11-18       Impact factor: 3.550

Review 5.  Pharmacogenomic Biomarkers for Improved Drug Therapy-Recent Progress and Future Developments.

Authors:  Volker M Lauschke; Lili Milani; Magnus Ingelman-Sundberg
Journal:  AAPS J       Date:  2017-11-27       Impact factor: 4.009

6.  Azathioprine-related myelosuppression in a patient homozygous for TPMT*3A.

Authors:  Pooja Budhiraja; Mordecai Popovtzer
Journal:  Nat Rev Nephrol       Date:  2011-06-28       Impact factor: 28.314

7.  Impact of methylenetetrahydrofolate reductase (MTHFR) polymorphisms on methotrexate-induced toxicities in acute lymphoblastic leukemia: a meta-analysis.

Authors:  Lin Yang; Xin Hu; Luhang Xu
Journal:  Tumour Biol       Date:  2012-04-20

8.  Exome sequencing and array-based comparative genomic hybridisation analysis of preferential 6-methylmercaptopurine producers.

Authors:  E W Chua; S Cree; M L Barclay; K Doudney; K Lehnert; A Aitchison; M A Kennedy
Journal:  Pharmacogenomics J       Date:  2015-03-10       Impact factor: 3.550

Review 9.  [Research advances in pharmacogenomics of mercaptopurine].

Authors:  Xiao-Xiao Chen; Shu-Hong Shen
Journal:  Zhongguo Dang Dai Er Ke Za Zhi       Date:  2017-09

10.  Impact of genetic polymorphisms on chemotherapy toxicity in childhood acute lymphoblastic leukemia.

Authors:  Guillermo Gervasini; Jose M Vagace
Journal:  Front Genet       Date:  2012-11-22       Impact factor: 4.599

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