BACKGROUND: It is unclear whether ethnic disparity of the prevalence of chronic kidney disease (CKD) exists among native Chinese and American ethnicities. METHODS: A stratified multistage clustered screening for CKD performed in Beijing in 2006 was compared with data from the National Health and Nutrition Examination Survey (NHANES) between 1999-2006 (participants aged > or =20 years, 13 626 Chinese, 9006 whites, 3447 African Americans, 4626 Hispanics). Serum creatinine from Beijing and NHANES were calibrated at the Cleveland Clinic Laboratory. The re-expressed abbreviated MDRD equation for Americans and its modified form for Chinese were used to estimate glomerular filtration rate (eGFR). Subjects with eGFR <60 mL/min/1.73 m(2) were diagnosed as having chronic renal insufficiency (CRI). Albuminuria was diagnosed if the urine albumin-creatinine ratio was >17 mg/g for males or >25 mg/g for females. CKD was diagnosed if CRI or albuminuria was present. RESULTS: Compared with American whites, African Americans and Hispanics, Chinese had a lower prevalence of adjusted albuminuria (12.10%, 16.33% and 14.16% versus 9.27%), CRI (9.46%, 5.18% and 3.11% versus 1.38%) and CKD (19.03%, 19.00% and 15.99% versus 10.25%). Moreover, Chinese hold the lowest risk of albuminuria when exposed to diabetes; the risk of CRI among Chinese when exposed to diabetes or hypertension was lower than that among African Americans, but similar to that among whites and Hispanics. CONCLUSIONS: The CKD prevalence was significantly different among native Chinese and American ethnicities.
BACKGROUND: It is unclear whether ethnic disparity of the prevalence of chronic kidney disease (CKD) exists among native Chinese and American ethnicities. METHODS: A stratified multistage clustered screening for CKD performed in Beijing in 2006 was compared with data from the National Health and Nutrition Examination Survey (NHANES) between 1999-2006 (participants aged > or =20 years, 13 626 Chinese, 9006 whites, 3447 African Americans, 4626 Hispanics). Serum creatinine from Beijing and NHANES were calibrated at the Cleveland Clinic Laboratory. The re-expressed abbreviated MDRD equation for Americans and its modified form for Chinese were used to estimate glomerular filtration rate (eGFR). Subjects with eGFR <60 mL/min/1.73 m(2) were diagnosed as having chronic renal insufficiency (CRI). Albuminuria was diagnosed if the urine albumin-creatinine ratio was >17 mg/g for males or >25 mg/g for females. CKD was diagnosed if CRI or albuminuria was present. RESULTS: Compared with American whites, African Americans and Hispanics, Chinese had a lower prevalence of adjusted albuminuria (12.10%, 16.33% and 14.16% versus 9.27%), CRI (9.46%, 5.18% and 3.11% versus 1.38%) and CKD (19.03%, 19.00% and 15.99% versus 10.25%). Moreover, Chinese hold the lowest risk of albuminuria when exposed to diabetes; the risk of CRI among Chinese when exposed to diabetes or hypertension was lower than that among African Americans, but similar to that among whites and Hispanics. CONCLUSIONS: The CKD prevalence was significantly different among native Chinese and American ethnicities.
Authors: David M Good; Petra Zürbig; Angel Argilés; Hartwig W Bauer; Georg Behrens; Joshua J Coon; Mohammed Dakna; Stéphane Decramer; Christian Delles; Anna F Dominiczak; Jochen H H Ehrich; Frank Eitner; Danilo Fliser; Moritz Frommberger; Arnold Ganser; Mark A Girolami; Igor Golovko; Wilfried Gwinner; Marion Haubitz; Stefan Herget-Rosenthal; Joachim Jankowski; Holger Jahn; George Jerums; Bruce A Julian; Markus Kellmann; Volker Kliem; Walter Kolch; Andrzej S Krolewski; Mario Luppi; Ziad Massy; Michael Melter; Christian Neusüss; Jan Novak; Karlheinz Peter; Kasper Rossing; Harald Rupprecht; Joost P Schanstra; Eric Schiffer; Jens-Uwe Stolzenburg; Lise Tarnow; Dan Theodorescu; Visith Thongboonkerd; Raymond Vanholder; Eva M Weissinger; Harald Mischak; Philippe Schmitt-Kopplin Journal: Mol Cell Proteomics Date: 2010-07-08 Impact factor: 5.911
Authors: Jie Zheng; Yuemiao Zhang; Humaira Rasheed; Venexia Walker; Yuka Sugawara; Jiachen Li; Yue Leng; Benjamin Elsworth; Robyn E Wootton; Si Fang; Qian Yang; Stephen Burgess; Philip C Haycock; Maria Carolina Borges; Yoonsu Cho; Rebecca Carnegie; Amy Howell; Jamie Robinson; Laurent F Thomas; Ben Michael Brumpton; Kristian Hveem; Stein Hallan; Nora Franceschini; Andrew P Morris; Anna Köttgen; Cristian Pattaro; Matthias Wuttke; Masayuki Yamamoto; Naoki Kashihara; Masato Akiyama; Masahiro Kanai; Koichi Matsuda; Yoichiro Kamatani; Yukinori Okada; Robin Walters; Iona Y Millwood; Zhengming Chen; George Davey Smith; Sean Barbour; Canqing Yu; Bjørn Olav Åsvold; Hong Zhang; Tom R Gaunt Journal: Int J Epidemiol Date: 2021-10-20 Impact factor: 7.196
Authors: Hui Miao; Linxin Liu; Yeli Wang; Yucheng Wang; Qile He; Tazeen Hasan Jafar; Shenglan Tang; Yi Zeng; John S Ji Journal: PLoS One Date: 2022-01-12 Impact factor: 3.240
Authors: Hilda O Hounkpatin; S Harris; Simon D S Fraser; Julie Day; Jennifer S Mindell; Maarten W Taal; Donal O'Donoghue; Paul J Roderick Journal: BMJ Open Date: 2020-08-13 Impact factor: 2.692