Literature DB >> 18983933

Micro- and nanofluidic systems for high-throughput biological screening.

Jongin Hong1, Joshua B Edel, Andrew J deMello.   

Abstract

High-throughput screening (HTS) is a method of scientific experimentation widely used in drug discovery and relevant to the fields of biology. The development of micro- and nanofluidic systems for use in the biological sciences has been driven by a range of fundamental attributes that accompany miniaturization and massively parallel experimentation. We review recent advances in both arraying strategies based on nano/microfluidics and novel nano/microfluidic devices with high analytical throughput rates.

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Year:  2008        PMID: 18983933     DOI: 10.1016/j.drudis.2008.10.001

Source DB:  PubMed          Journal:  Drug Discov Today        ISSN: 1359-6446            Impact factor:   7.851


  31 in total

Review 1.  Phenotyping patient-derived cells for translational studies in cardiovascular disease.

Authors:  Stanley Y Shaw; Ari D Brettman
Journal:  Circulation       Date:  2011-11-29       Impact factor: 29.690

2.  Microfluidics: Analog-to-digital drug screening.

Authors:  Robert C R Wootton; Andrew J Demello
Journal:  Nature       Date:  2012-02-29       Impact factor: 49.962

3.  Protein denaturation and protein:drugs interactions from intrinsic protein fluorescence measurements at the nanolitre scale.

Authors:  Matthieu Gaudet; Nina Remtulla; Sophie E Jackson; Ewan R G Main; Daniel G Bracewell; Gabriel Aeppli; Paul A Dalby
Journal:  Protein Sci       Date:  2010-08       Impact factor: 6.725

Review 4.  Microfluidics-to-mass spectrometry: a review of coupling methods and applications.

Authors:  Xue Wang; Lian Yi; Nikita Mukhitov; Adrian M Schrell; Raghuram Dhumpa; Michael G Roper
Journal:  J Chromatogr A       Date:  2014-10-23       Impact factor: 4.759

5.  Multifunctional, inexpensive, and reusable nanoparticle-printed biochip for cell manipulation and diagnosis.

Authors:  Rahim Esfandyarpour; Matthew J DiDonato; Yuxin Yang; Naside Gozde Durmus; James S Harris; Ronald W Davis
Journal:  Proc Natl Acad Sci U S A       Date:  2017-02-06       Impact factor: 11.205

Review 6.  Analysis of individual molecular events of DNA damage response by flow- and image-assisted cytometry.

Authors:  Zbigniew Darzynkiewicz; Frank Traganos; Hong Zhao; H Dorota Halicka; Joanna Skommer; Donald Wlodkowic
Journal:  Methods Cell Biol       Date:  2011       Impact factor: 1.441

7.  A microfluidic-based electrochemical biochip for label-free DNA hybridization analysis.

Authors:  Hadar Ben-Yoav; Peter H Dykstra; Tanya Gordonov; William E Bentley; Reza Ghodssi
Journal:  J Vis Exp       Date:  2014-09-10       Impact factor: 1.355

8.  Automated Lead Optimization of MMP-12 Inhibitors Using a Genetic Algorithm.

Authors:  Stephen D Pickett; Darren V S Green; David L Hunt; David A Pardoe; Ian Hughes
Journal:  ACS Med Chem Lett       Date:  2010-10-20       Impact factor: 4.345

9.  Molecularly imprinted electrochemical sensing of urinary melatonin in a microfluidic system.

Authors:  Mei-Hwa Lee; Danny O'Hare; Yi-Li Chen; Yu-Chia Chang; Chien-Hsin Yang; Bin-Da Liu; Hung-Yin Lin
Journal:  Biomicrofluidics       Date:  2014-10-15       Impact factor: 2.800

10.  Temperature sculpting in yoctoliter volumes.

Authors:  Joseph E Reiner; Joseph W F Robertson; Daniel L Burden; Lisa K Burden; Arvind Balijepalli; John J Kasianowicz
Journal:  J Am Chem Soc       Date:  2013-02-14       Impact factor: 15.419

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