Literature DB >> 18979475

New insights into the mechanism of enzymatic chlorination of tryptophan.

Silvana Flecks1, Eugenio P Patallo, Xiaofeng Zhu, Aliz J Ernyei, Gotthard Seifert, Alexander Schneider, Changjiang Dong, James H Naismith, Karl-Heinz van Pée.   

Abstract

Entities:  

Mesh:

Substances:

Year:  2008        PMID: 18979475      PMCID: PMC3326536          DOI: 10.1002/anie.200802466

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN: 1433-7851            Impact factor:   15.336


× No keyword cloud information.
  12 in total

1.  A regioselective tryptophan 5-halogenase is involved in pyrroindomycin biosynthesis in Streptomyces rugosporus LL-42D005.

Authors:  Susanne Zehner; Alexander Kotzsch; Bojan Bister; Roderich D Süssmuth; Carmen Méndez; José A Salas; Karl-Heinz van Pée
Journal:  Chem Biol       Date:  2005-04

2.  A general method of in vitro preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions.

Authors:  R Higuchi; B Krummel; R K Saiki
Journal:  Nucleic Acids Res       Date:  1988-08-11       Impact factor: 16.971

3.  Four genes from Pseudomonas fluorescens that encode the biosynthesis of pyrrolnitrin.

Authors:  P E Hammer; D S Hill; S T Lam; K H Van Pée; J M Ligon
Journal:  Appl Environ Microbiol       Date:  1997-06       Impact factor: 4.792

4.  Kinetic analysis of the role of histidine chloramines in hypochlorous acid mediated protein oxidation.

Authors:  David I Pattison; Michael J Davies
Journal:  Biochemistry       Date:  2005-05-17       Impact factor: 3.162

5.  A genomic screening approach to the structure-guided identification of drug candidates from natural sources.

Authors:  Andreas Hornung; Marcelo Bertazzo; Agnieszka Dziarnowski; Kathrin Schneider; Katrin Welzel; Sven-Eric Wohlert; Meike Holzenkämpfer; Graeme J Nicholson; Andreas Bechthold; Roderich D Süssmuth; Andreas Vente; Stefan Pelzer
Journal:  Chembiochem       Date:  2007-05-07       Impact factor: 3.164

6.  Chlorination by a long-lived intermediate in the mechanism of flavin-dependent halogenases.

Authors:  Ellen Yeh; Leah C Blasiak; Alexander Koglin; Catherine L Drennan; Christopher T Walsh
Journal:  Biochemistry       Date:  2007-02-06       Impact factor: 3.162

7.  Robust in vitro activity of RebF and RebH, a two-component reductase/halogenase, generating 7-chlorotryptophan during rebeccamycin biosynthesis.

Authors:  Ellen Yeh; Sylvie Garneau; Christopher T Walsh
Journal:  Proc Natl Acad Sci U S A       Date:  2005-03-02       Impact factor: 11.205

Review 8.  Peroxidase-catalyzed halogenation.

Authors:  M Morrison; G R Schonbaum
Journal:  Annu Rev Biochem       Date:  1976       Impact factor: 23.643

9.  Regiospecific chlorination of (S)-beta-tyrosyl-S-carrier protein catalyzed by SgcC3 in the biosynthesis of the enediyne antitumor antibiotic C-1027.

Authors:  Shuangjun Lin; Steven G Van Lanen; Ben Shen
Journal:  J Am Chem Soc       Date:  2007-09-22       Impact factor: 15.419

10.  Dichlorination of a pyrrolyl-S-carrier protein by FADH2-dependent halogenase PltA during pyoluteorin biosynthesis.

Authors:  Pieter C Dorrestein; Ellen Yeh; Sylvie Garneau-Tsodikova; Neil L Kelleher; Christopher T Walsh
Journal:  Proc Natl Acad Sci U S A       Date:  2005-09-14       Impact factor: 11.205

View more
  32 in total

Review 1.  Enzymatic functionalization of carbon-hydrogen bonds.

Authors:  Jared C Lewis; Pedro S Coelho; Frances H Arnold
Journal:  Chem Soc Rev       Date:  2010-11-15       Impact factor: 54.564

2.  Expression, purification and preliminary diffraction studies of CmlS.

Authors:  Ryan Latimer; Kateryna Podzelinska; Alexei Soares; Anupam Bhattacharya; Leo C Vining; Zongchao Jia; David L Zechel
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2009-02-26

3.  The ternary complex of PrnB (the second enzyme in the pyrrolnitrin biosynthesis pathway), tryptophan, and cyanide yields new mechanistic insights into the indolamine dioxygenase superfamily.

Authors:  Xiaofeng Zhu; Karl-Heinz van Pée; James H Naismith
Journal:  J Biol Chem       Date:  2010-04-26       Impact factor: 5.157

Review 4.  Enzymatic Halogenation and Dehalogenation Reactions: Pervasive and Mechanistically Diverse.

Authors:  Vinayak Agarwal; Zachary D Miles; Jaclyn M Winter; Alessandra S Eustáquio; Abrahim A El Gamal; Bradley S Moore
Journal:  Chem Rev       Date:  2017-01-20       Impact factor: 60.622

5.  Two Flavoenzymes Catalyze the Post-Translational Generation of 5-Chlorotryptophan and 2-Aminovinyl-Cysteine during NAI-107 Biosynthesis.

Authors:  Manuel A Ortega; Dillon P Cogan; Subha Mukherjee; Neha Garg; Bo Li; Gabrielle N Thibodeaux; Sonia I Maffioli; Stefano Donadio; Margherita Sosio; Jerome Escano; Leif Smith; Satish K Nair; Wilfred A van der Donk
Journal:  ACS Chem Biol       Date:  2017-01-13       Impact factor: 5.100

6.  Divergent pathways in the biosynthesis of bisindole natural products.

Authors:  Katherine S Ryan; Catherine L Drennan
Journal:  Chem Biol       Date:  2009-04-24

7.  Regioselective arene halogenation using the FAD-dependent halogenase RebH.

Authors:  James T Payne; Mary C Andorfer; Jared C Lewis
Journal:  Angew Chem Int Ed Engl       Date:  2013-04-16       Impact factor: 15.336

8.  Structural insights into regioselectivity in the enzymatic chlorination of tryptophan.

Authors:  Xiaofeng Zhu; Walter De Laurentis; Khim Leang; Julia Herrmann; Katja Ihlefeld; Karl-Heinz van Pée; James H Naismith
Journal:  J Mol Biol       Date:  2009-06-06       Impact factor: 5.469

Review 9.  Understanding and Improving the Activity of Flavin-Dependent Halogenases via Random and Targeted Mutagenesis.

Authors:  Mary C Andorfer; Jared C Lewis
Journal:  Annu Rev Biochem       Date:  2018-03-28       Impact factor: 23.643

10.  Understanding Flavin-Dependent Halogenase Reactivity via Substrate Activity Profiling.

Authors:  Mary C Andorfer; Jonathan E Grob; Christine E Hajdin; Julia R Chael; Piro Siuti; Jeremiah Lilly; Kian L Tan; Jared C Lewis
Journal:  ACS Catal       Date:  2017-01-31       Impact factor: 13.084

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.