Literature DB >> 18978919

Real time en face Fourier-domain optical coherence tomography with direct hardware frequency demodulation.

Benjamin R Biedermann1, Wolfgang Wieser, Christoph M Eigenwillig, Gesa Palte, Desmond C Adler, Vivek J Srinivasan, James G Fujimoto, Robert Huber.   

Abstract

We demonstrate en face swept source optical coherence tomography (ss-OCT) without requiring a Fourier transformation step. The electronic optical coherence tomography (OCT) interference signal from a k-space linear Fourier domain mode-locked laser is mixed with an adjustable local oscillator, yielding the analytic reflectance signal from one image depth for each frequency sweep of the laser. Furthermore, a method for arbitrarily shaping the spectral intensity profile of the laser is presented, without requiring the step of numerical apodization. In combination, these two techniques enable sampling of the in-phase and quadrature signal with a slow analog-to-digital converter and allow for real-time display of en face projections even for highest axial scan rates. Image data generated with this technique is compared to en face images extracted from a three-dimensional OCT data set. This technique can allow for real-time visualization of arbitrarily oriented en face planes for the purpose of alignment, registration, or operator-guided survey scans while simultaneously maintaining the full capability of high-speed volumetric ss-OCT functionality.

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Mesh:

Year:  2008        PMID: 18978919      PMCID: PMC2743229          DOI: 10.1364/ol.33.002556

Source DB:  PubMed          Journal:  Opt Lett        ISSN: 0146-9592            Impact factor:   3.776


  15 in total

1.  115 kHz tuning repetition rate ultrahigh-speed wavelength-swept semiconductor laser.

Authors:  W Y Oh; S H Yun; G J Tearney; B E Bouma
Journal:  Opt Lett       Date:  2005-12-01       Impact factor: 3.776

2.  Buffered Fourier domain mode locking: Unidirectional swept laser sources for optical coherence tomography imaging at 370,000 lines/s.

Authors:  Robert Huber; Desmond C Adler; James G Fujimoto
Journal:  Opt Lett       Date:  2006-10-15       Impact factor: 3.776

3.  Full-field optical coherence microscopy.

Authors:  E Beaurepaire; A C Boccara; M Lebec; L Blanchot; H Saint-Jalmes
Journal:  Opt Lett       Date:  1998-02-15       Impact factor: 3.776

4.  Sensitivity advantage of swept source and Fourier domain optical coherence tomography.

Authors:  Michael Choma; Marinko Sarunic; Changhuei Yang; Joseph Izatt
Journal:  Opt Express       Date:  2003-09-08       Impact factor: 3.894

5.  Performance of fourier domain vs. time domain optical coherence tomography.

Authors:  R Leitgeb; C Hitzenberger; Adolf Fercher
Journal:  Opt Express       Date:  2003-04-21       Impact factor: 3.894

6.  Simultaneous acquisition of sectional and fundus ophthalmic images with spectral-domain optical coherence tomography.

Authors:  Shuliang Jiao; Robert Knighton; Xiangrun Huang; Giovanni Gregori; Carmen Puliafito
Journal:  Opt Express       Date:  2005-01-24       Impact factor: 3.894

7.  K-space linear Fourier domain mode locked laser and applications for optical coherence tomography.

Authors:  Christoph M Eigenwillig; Benjamin R Biedermann; Gesa Palte; Robert Huber
Journal:  Opt Express       Date:  2008-06-09       Impact factor: 3.894

8.  Swept source optical coherence microscopy using a Fourier domain mode-locked laser.

Authors:  Shu-Wei Huang; Aaron D Aguirre; Robert A Huber; Desmond C Adler; James G Fujimoto
Journal:  Opt Express       Date:  2007-05-14       Impact factor: 3.894

9.  Optical coherence microscopy in scattering media.

Authors:  J A Izatt; M R Hee; G M Owen; E A Swanson; J G Fujimoto
Journal:  Opt Lett       Date:  1994-04-15       Impact factor: 3.776

10.  Optical coherence tomography.

Authors:  D Huang; E A Swanson; C P Lin; J S Schuman; W G Stinson; W Chang; M R Hee; T Flotte; K Gregory; C A Puliafito
Journal:  Science       Date:  1991-11-22       Impact factor: 47.728

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  11 in total

1.  Master slave en-face OCT/SLO.

Authors:  Adrian Bradu; Konstantin Kapinchev; Frederick Barnes; Adrian Podoleanu
Journal:  Biomed Opt Express       Date:  2015-08-27       Impact factor: 3.732

2.  Imaging the eye fundus with real-time en-face spectral domain optical coherence tomography.

Authors:  Adrian Bradu; Adrian Gh Podoleanu
Journal:  Biomed Opt Express       Date:  2014-03-19       Impact factor: 3.732

3.  Ultra-widefield retinal MHz-OCT imaging with up to 100 degrees viewing angle.

Authors:  Jan Philip Kolb; Thomas Klein; Corinna L Kufner; Wolfgang Wieser; Aljoscha S Neubauer; Robert Huber
Journal:  Biomed Opt Express       Date:  2015-04-02       Impact factor: 3.732

4.  Single pulse two photon fluorescence lifetime imaging (SP-FLIM) with MHz pixel rate.

Authors:  Matthias Eibl; Sebastian Karpf; Daniel Weng; Hubertus Hakert; Tom Pfeiffer; Jan Philip Kolb; Robert Huber
Journal:  Biomed Opt Express       Date:  2017-06-01       Impact factor: 3.732

Review 5.  High-speed OCT light sources and systems [Invited].

Authors:  Thomas Klein; Robert Huber
Journal:  Biomed Opt Express       Date:  2017-01-13       Impact factor: 3.732

6.  Real-time 4D signal processing and visualization using graphics processing unit on a regular nonlinear-k Fourier-domain OCT system.

Authors:  Kang Zhang; Jin U Kang
Journal:  Opt Express       Date:  2010-05-24       Impact factor: 3.894

7.  Investigation of the impact of water absorption on retinal OCT imaging in the 1060 nm range.

Authors:  Sebastian Marschall; Christian Pedersen; Peter E Andersen
Journal:  Biomed Opt Express       Date:  2012-06-18       Impact factor: 3.732

8.  Enface Thickness Mapping and Reflectance Imaging of Retinal Layers in Diabetic Retinopathy.

Authors:  Andrew W Francis; Justin Wanek; Jennifer I Lim; Mahnaz Shahidi
Journal:  PLoS One       Date:  2015-12-23       Impact factor: 3.240

9.  Alterations in Retinal Layer Thickness and Reflectance at Different Stages of Diabetic Retinopathy by En Face Optical Coherence Tomography.

Authors:  Justin Wanek; Norman P Blair; Felix Y Chau; Jennifer I Lim; Yannek I Leiderman; Mahnaz Shahidi
Journal:  Invest Ophthalmol Vis Sci       Date:  2016-07-01       Impact factor: 4.799

10.  Extended coherence length megahertz FDML and its application for anterior segment imaging.

Authors:  Wolfgang Wieser; Thomas Klein; Desmond C Adler; Francois Trépanier; Christoph M Eigenwillig; Sebastian Karpf; Joseph M Schmitt; Robert Huber
Journal:  Biomed Opt Express       Date:  2012-09-24       Impact factor: 3.732

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