Literature DB >> 18977139

Synthesis and in vitro evaluation of the antifungal activities of dihydropyrimidinones.

Okram Mukherjee Singh1, Sarangthem Joychandra Singh, Mutum Babita Devi, Laitonjam Nalini Devi, Nameirakpam Irabanta Singh, Sang-Gyeong Lee.   

Abstract

Copper (II) chloride in the absence of any solvent, efficiently catalyses the synthesis of dihydropyrimidinones (80-96% yields) by the Biginelli reaction. Six compounds were selected and examined their antifungal activities against the radial growth of three fungal species viz., Trichoderma hammatum, Trichoderma koningii and Aspergillus niger.

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Year:  2008        PMID: 18977139     DOI: 10.1016/j.bmcl.2008.10.063

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  3 in total

Review 1.  Recent developments in the synthesis and applications of dihydropyrimidin-2(1H)-ones and thiones.

Authors:  Behzad Mohammadi; Farahnaz K Behbahani
Journal:  Mol Divers       Date:  2018-01-18       Impact factor: 2.943

2.  Synthesis and molecular modelling studies of pyrimidinones and pyrrolo[3,4-d]-pyrimidinodiones as new antiplasmodial compounds.

Authors:  Kamilla Rodrigues Rogerio; Leonardo J M Carvalho; Luiza Helena Pinto Domingues; Bruno Junior Neves; José Teófilo Moreira Filho; Rosane Nora Castro; Cesare Bianco Júnior; Claudio Tadeu Daniel-Ribeiro; Carolina Horta Andrade; Cedric Stephan Graebin
Journal:  Mem Inst Oswaldo Cruz       Date:  2018-06-18       Impact factor: 2.743

3.  Antimicrobial evaluation of some novel derivatives of 3,4-dihydropyrimidine-2(1H)-one.

Authors:  M Jalali; M Mahdavi; H R Memarian; M Ranjbar; M Soleymani; A Fassihi; D Abedi
Journal:  Res Pharm Sci       Date:  2012-10
  3 in total

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