Literature DB >> 18973861

Dosimetric comparison of tandem and Ovoids vs. tandem and ring for intracavitary gynecologic applications.

Daphne Levin1, Janna Menhel, Tanya Rabin, M Raphael Pfeffer, Zvi Symon.   

Abstract

We evaluated dosimetric differences in tandem and ovoid (TO) and tandem and ring (TR) gynecologic brachytherapy applicators. Seventeen patients with cervical cancer (Stages II-IV) receiving 3 high-dose-rate (HDR) brachytherapy applications (both TO and TR) were studied. Patients underwent computed tomography (CT) scans with contrast in bladder, and were prescribed 8 Gy to ICRU points A, with additional optimization goals of maintaining the pear-shaped dose distribution and minimizing bladder and rectum doses. Bladder and rectum point doses, mean, and maximum doses were calculated. Total treatment time and volumes treated to 95%, 85%, 50%, and 20% or the prescription dose were compared. There were no significant differences between TO and TR applicators in doses to prescription points or critical organs. However, there were significant differences (p < 0.001) between the applicators in treated volumes and total treatment time. The TO treated larger volumes over a longer time. Within each patient, when the applicators were compared, treated volumes were also found to be significantly different (p < 0.01, chi(2)). Our results demonstrate that the 2 applicators, while delivering the prescribed dose to points A and keeping critical organ doses below tolerance, treat significantly different volumes. It is unclear if this difference is clinically meaningful. TO applicators may be treating surrounding healthy tissue unnecessarily, or TR applicators may be underdosing tumor tissue. Further investigation with appropriate imaging modalities is required for accurate delineation of target volumes. Clearly, the TO and TR are not identical, and should not be used interchangeably without further study.

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Year:  2008        PMID: 18973861     DOI: 10.1016/j.meddos.2008.06.003

Source DB:  PubMed          Journal:  Med Dosim        ISSN: 1873-4022            Impact factor:   1.482


  7 in total

1.  Short-term clinical outcome and dosimetric comparison of tandem and ring versus tandem and ovoids intracavitary applicators.

Authors:  John K Ma; Waleed F Mourad; Robert Allbright; Satyaseelan Packianathan; Leslie M Harrell; Edmund Chinchar; Alex Nguyen; Srinivasan Vijayakumar
Journal:  J Contemp Brachytherapy       Date:  2015-05-28

2.  Dose to pelvic lymph nodes in locally advanced cervical cancer during high-dose-rate brachytherapy with tandem-ring applicators.

Authors:  Mona Malekzadeh Moghani; Zahra Siavashpour; Oleksander Ogorodniitchouk; Pablo Moreno-Acosta; Delphine Plattard; Alexis Vallard; Sandrine Sotton; Wafa Bouleftour; Julien Langrand-Escure; Nicolas Magné
Journal:  J Contemp Brachytherapy       Date:  2022-04-06

3.  A comparison of dosimetric parameters in high-dose-rate intracavitary brachytherapy using tandem and ring applicators: is the combination of a rectal retractor and radio-opaque vaginal packing better than rectal retractor alone for rectum sparing in cervical cancer?

Authors:  Siddharth Vats; Shabnum Thakur; Mukesh Sharma; Manish Gupta; Lalit Chandrakant; Muninder Negi; Swati Verma; Anup Negi; Vivek Kumar; Parul Sharma; Rattan Mahesh Negi
Journal:  Ecancermedicalscience       Date:  2022-08-08

4.  Dosimetric evaluation of image based brachytherapy using tandem ovoid and tandem ring applicators.

Authors:  Ramya Rangarajan
Journal:  Rep Pract Oncol Radiother       Date:  2018-01-12

5.  Comparison of dose volume parameters evaluated using three forward planning - optimization techniques in cervical cancer brachytherapy involving two applicators.

Authors:  Bikramjit Chakrabarti; Somapriya Basu-Roy; Sanjay Kumar Kar; Sounik Das; Annesha Lahiri
Journal:  J Contemp Brachytherapy       Date:  2017-10-10

6.  A comparison of tandem ring and tandem ovoid treatment as a curative brachytherapy component for cervical cancer.

Authors:  Sukriye Bilge Gursel; Alparslan Serarslan; Ahmet Deniz Meydan; Nilgun Okumus; Tenzile Yasayacak
Journal:  J Contemp Brachytherapy       Date:  2020-04-08

7.  Dosimetric comparison of two different applicators and rectal retraction methods used in inverse optimization-based intracavitary brachytherapy for cervical cancer.

Authors:  Fatih Biltekin; Melis Gultekin; Melek Tugce Yilmaz; Ferah Yildiz
Journal:  J Contemp Brachytherapy       Date:  2020-02-28
  7 in total

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