Literature DB >> 18967148

Metallothioneins: historical review and state of knowledge.

M Nordberg1.   

Abstract

The history of metallothionein (MT) research is reviewed. Various methods for isolation, characterisation and quantification are evaluated. The role of MT in metal metabolism and toxicity is explained. Gender differences and polymorphisms are brought to the attention of the reader and the possible relationship with disease is discussed. The review is an evaluation based on data from literature and from own original experimental data. Future aspects on research within the MT field is stressed.

Entities:  

Year:  1998        PMID： 18967148     DOI： 10.1016/s0039-9140(97)00345-7

Source DB:  PubMed          Journal:  Talanta        ISSN： 0039-9140            Impact factor:   6.057


  16 in total

1.  The effects of metallothionein 2A polymorphism on lead metabolism: are pregnant women with a heterozygote genotype for metallothionein 2A polymorphism and their newborns at risk of having higher blood lead levels?

Authors:  Deniz Tekin; Zeliha Kayaaltı; Tülin Söylemezoğlu
Journal:  Int Arch Occup Environ Health       Date:  2011-10-18       Impact factor: 3.015

Review 2.  In situ imaging of metals in cells and tissues.

Authors:  Reagan McRae; Pritha Bagchi; S Sumalekshmy; Christoph J Fahrni
Journal:  Chem Rev       Date:  2009-10       Impact factor: 60.622

3.  Bioaccumulation, morphological changes, and induction of metallothionein gene expression in the digestive system of the freshwater crab Sinopotamon henanense after exposure to cadmium.

Authors:  Hao Wu; Yingjun Li; Xingping Lang; Lan Wang
Journal:  Environ Sci Pollut Res Int       Date:  2015-04-07       Impact factor: 4.223

4.  Functional characterization of four metallothionein genes in Daphnia pulex exposed to environmental stressors.

Authors:  J Asselman; S P Glaholt; Z Smith; G Smagghe; C R Janssen; J K Colbourne; J R Shaw; K A C De Schamphelaere
Journal:  Aquat Toxicol       Date:  2011-12-29       Impact factor: 4.964

5.  Metallothionein gene expression in peripheral lymphocytes from cadmium-exposed workers.

Authors:  J Lu; T Jin; G Nordberg; M Nordberg
Journal:  Cell Stress Chaperones       Date:  2001-04       Impact factor: 3.667

Review 6.  Roles of zinc and metallothionein-3 in oxidative stress-induced lysosomal dysfunction, cell death, and autophagy in neurons and astrocytes.

Authors:  Sook-Jeong Lee; Jae-Young Koh
Journal:  Mol Brain       Date:  2010-10-26       Impact factor: 4.041

7.  Evaluation of eight plasma proteins as candidate blood-based biomarkers for malignant gliomas.

Authors:  Ryan P Lange; Allen Everett; Pratima Dulloor; Frederick K Korley; Chetan Bettegowda; Cherie Blair; Stuart A Grossman; Matthias Holdhoff
Journal:  Cancer Invest       Date:  2014-07-14       Impact factor: 2.176

8.  Zinc hyperaccumulation in squirrelfish (Holocentrus adscenscionis) and its role in embryo viability.

Authors:  E David Thompson; Gregory D Mayer; Chris N Glover; Tom Capo; Patrick J Walsh; Christer Hogstrand
Journal:  PLoS One       Date:  2012-10-04       Impact factor: 3.240

9.  Apoptosis, metallothionein, and bioavailable metals in domestic mice (Mus musculus L.) from a human-inhabited volcanic area.

Authors:  André Amaral; Carolina Cabral; Cláudia Guedes; Armindo Rodrigues
Journal:  Ecotoxicology       Date:  2007-06-23       Impact factor: 2.935

Review 10.  Metallothionein and Cadmium Toxicology-Historical Review and Commentary.

Authors:  Monica Nordberg; Gunnar F Nordberg
Journal:  Biomolecules       Date:  2022-02-24
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