Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Evaluation of eight plasma proteins as candidate blood-based biomarkers for malignant gliomas.

Literature DB >> 25019213

Evaluation of eight plasma proteins as candidate blood-based biomarkers for malignant gliomas.

Ryan P Lange¹, Allen Everett, Pratima Dulloor, Frederick K Korley, Chetan Bettegowda, Cherie Blair, Stuart A Grossman, Matthias Holdhoff.

Abstract

Eight brain-derived proteins were evaluated regarding their potential for further development as a blood-based biomarker for malignant gliomas. Plasma levels for glial fibrillary acidic protein, neurogranin, brain-derived neurotrophic factor, intracellular adhesion molecule 5, metallothionein-3, beta-synuclein, S100 and neuron specific enolase were tested in plasma of 23 patients with high-grade gliomas (WHO grade IV), 11 low-grade gliomas (WHO grade II), and 15 healthy subjects. Compared to the healthy controls, none of the proteins appeared to be specific for glioblastomas. However, the data are suggestive of higher protein levels in gliosarcomas (n = 2), which may deserve further exploration.

Entities: CellLine Chemical Disease Gene Mutation Species

Keywords: Brain Tumors; Cancer Biomarkers; Circulating Biomarkers; Glioma; Proteins

Mesh：

Substances：

Year: 2014 PMID： 25019213 PMCID： PMC4322939 DOI： 10.3109/07357907.2014.933237

Source DB: PubMed Journal: Cancer Invest ISSN： 0735-7907 Impact factor: 2.176

59 in total

1. GFAP and S100B are biomarkers of traumatic brain injury: an observational cohort study.

Authors: P E Vos; B Jacobs; T M J C Andriessen; K J B Lamers; G F Borm; T Beems; M Edwards; C F Rosmalen; J L M Vissers
Journal: Neurology Date: 2010-11-16 Impact factor: 9.910

2. Volatile anesthetics reduce biochemical markers of brain injury and brain magnesium disorders in patients undergoing coronary artery bypass graft surgery.

Authors: Wojciech Dabrowski; Ziemowit Rzecki; Marek Czajkowski; Jacek Pilat; Piotr Wacinski; Edyta Kotlinska; Małgorzata Sztanke; Krzysztof Sztanke; Krzysztof Stazka; Kazimierz Pasternak
Journal: J Cardiothorac Vasc Anesth Date: 2011-12-28 Impact factor: 2.628

Review 3. Glial fibrillary acidic protein: GFAP-thirty-one years (1969-2000).

Authors: L F Eng; R S Ghirnikar; Y L Lee
Journal: Neurochem Res Date: 2000-10 Impact factor: 3.996

4. Ischemia induces metallothionein III expression in neurons of rat brain.

Authors: S Yanagitani; H Miyazaki; Y Nakahashi; K Kuno; Y Ueno; M Matsushita; Y Naitoh; S Taketani; K Inoue
Journal: Life Sci Date: 1999 Impact factor: 5.037

5. Expression of metallothionein-III in patients with non-small cell lung cancer.

Authors: Bozena Werynska; Bartosz Pula; Beata Muszczynska-Bernhard; Agnieszka Gomulkiewicz; Aleksandra Jethon; Marzena Podhorska-Okolow; Renata Jankowska; Piotr Dziegiel
Journal: Anticancer Res Date: 2013-03 Impact factor: 2.480

Review 6. ICAM-5--a novel two-facetted adhesion molecule in the mammalian brain.

Authors: Carl G Gahmberg; Li Tian; Lin Ning; Henrietta Nyman-Huttunen
Journal: Immunol Lett Date: 2008-03-10 Impact factor: 3.685

7. Possible relation of hemin-induced HO-1 expression to the upregulation of VEGF and BDNF mRNA levels in rat C6 glioma cells.

Authors: Kyoji Morita; Mi-Sook Lee; Song Her
Journal: J Mol Neurosci Date: 2008-10-21 Impact factor: 3.444

8. Increased plasma levels of brain derived neurotrophic factor (BDNF) after multiple sclerosis relapse.

Authors: Elizabeth Regina Comini Frota; David Henrique Rodrigues; Eduardo Antonio Donadi; Doralina G Brum; Damacio Ramon Kaimen Maciel; Antônio Lúcio Teixeira
Journal: Neurosci Lett Date: 2009-05-27 Impact factor: 3.046

Review 9. Tumour markers in colorectal cancer: European Group on Tumour Markers (EGTM) guidelines for clinical use.

Authors: M J Duffy; A van Dalen; C Haglund; L Hansson; E Holinski-Feder; R Klapdor; R Lamerz; P Peltomaki; C Sturgeon; O Topolcan
Journal: Eur J Cancer Date: 2007-05-18 Impact factor: 9.162

Review 10. The synucleins.

Authors: Julia M George
Journal: Genome Biol Date: 2001-12-20 Impact factor: 13.583

9 in total

Review 1. Preoperative Diagnosis and Molecular Characterization of Gliomas With Liquid Biopsy and Radiogenomics.

Authors: Carmen Balana; Sara Castañer; Cristina Carrato; Teresa Moran; Assumpció Lopez-Paradís; Marta Domenech; Ainhoa Hernandez; Josep Puig
Journal: Front Neurol Date: 2022-05-26 Impact factor: 4.086

Review 2. Circulating biomarkers for gliomas.

Authors: Manfred Westphal; Katrin Lamszus
Journal: Nat Rev Neurol Date: 2015-09-15 Impact factor: 42.937

Review 3. Blood GFAP as an emerging biomarker in brain and spinal cord disorders.

Authors: Ahmed Abdelhak; Matteo Foschi; Samir Abu-Rumeileh; John K Yue; Lucio D'Anna; Andre Huss; Patrick Oeckl; Albert C Ludolph; Jens Kuhle; Axel Petzold; Geoffrey T Manley; Ari J Green; Markus Otto; Hayrettin Tumani
Journal: Nat Rev Neurol Date: 2022-02-03 Impact factor: 44.711

4. Liquid biopsies in patients with diffuse glioma.

Authors: Myron G Best; Nik Sol; Sebastiaan Zijl; Jaap C Reijneveld; Pieter Wesseling; Thomas Wurdinger
Journal: Acta Neuropathol Date: 2015-02-27 Impact factor: 17.088

5. Derivation of a Three Biomarker Panel to Improve Diagnosis in Patients with Mild Traumatic Brain Injury.

Authors: W Frank Peacock; Timothy E Van Meter; Nazanin Mirshahi; Kyle Ferber; Robert Gerwien; Vani Rao; Haris Iqbal Sair; Ramon Diaz-Arrastia; Frederick K Korley
Journal: Front Neurol Date: 2017-11-30 Impact factor: 4.003

Review 6. Current and Future Trends on Diagnosis and Prognosis of Glioblastoma: From Molecular Biology to Proteomics.

Authors: Artemiy S Silantyev; Luca Falzone; Massimo Libra; Olga I Gurina; Karina Sh Kardashova; Taxiarchis K Nikolouzakis; Alexander E Nosyrev; Christopher W Sutton; Panayiotis D. Mitsias; Aristides Tsatsakis
Journal: Cells Date: 2019-08-09 Impact factor: 6.600