Literature DB >> 18955529

Genotypic versus phenotypic characterization, with respect to beta-lactam susceptibility, of Haemophilus influenzae isolates exhibiting decreased susceptibility to beta-lactam resistance markers.

David Sevillano1, María-José Giménez, Emilia Cercenado, Fabio Cafini, Amadeo Gené, Luis Alou, Francesc Marco, Luis Martínez-Martínez, Pilar Coronel, Lorenzo Aguilar.   

Abstract

Among 165 Spanish Haemophilus influenzae isolates with mutations in the ftsI gene (ftsI(+)) (2005 to 2007), 73% were beta-lactamase negative and 26.7% were positive. The proportion of beta-lactamase-negative isolates to beta-lactamase-positive isolates was 2:1 to 4:1 in general, versus 1:3 in pediatric hospitals. Among 44 beta-lactamase-positive strains, 8 strains produced ROB-1 (5 from the pediatric hospital). beta-Lactamase-positive ftsI(+) strains were phylogenetically closer than were beta-lactamase-negative strains.

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Year:  2008        PMID： 18955529      PMCID： PMC2612133          DOI： 10.1128/AAC.00402-08

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  7 in total

1.  Association of amino acid substitutions in penicillin-binding protein 3 with beta-lactam resistance in beta-lactamase-negative ampicillin-resistant Haemophilus influenzae.

Authors:  K Ubukata; Y Shibasaki; K Yamamoto; N Chiba; K Hasegawa; Y Takeuchi; K Sunakawa; M Inoue; M Konno
Journal:  Antimicrob Agents Chemother       Date:  2001-06       Impact factor: 5.191

2.  Genetic and molecular characterization of beta-lactamase-negative ampicillin-resistant Haemophilus influenzae with unusually high resistance to ampicillin.

Authors:  Frank S Kaczmarek; Thomas D Gootz; Fadia Dib-Hajj; Wenchi Shang; Shawn Hallowell; Melissa Cronan
Journal:  Antimicrob Agents Chemother       Date:  2004-05       Impact factor: 5.191

3.  Influence of Haemophilus influenzae beta-lactamase production and/or ftsI gene mutations on in vitro activity of and susceptibility rates to aminopenicillins and second- and third-generation cephalosporins.

Authors:  J García-de-Lomas; M Lerma; L Cebrián; J L Juan-Bañón; P Coronel; M J Giménez; L Aguilar
Journal:  Int J Antimicrob Agents       Date:  2007-04-25       Impact factor: 5.283

4.  Determination of antimicrobial susceptibilities of Canadian isolates of Haemophilus influenzae and characterization of their beta-lactamases. Canadian Haemophilus Study Group.

Authors:  S R Scriver; S L Walmsley; C L Kau; D J Hoban; J Brunton; A McGeer; T C Moore; E Witwicki
Journal:  Antimicrob Agents Chemother       Date:  1994-07       Impact factor: 5.191

5.  Ampicillin-resistant non-beta-lactamase-producing Haemophilus influenzae in Spain: recent emergence of clonal isolates with increased resistance to cefotaxime and cefixime.

Authors:  Silvia García-Cobos; José Campos; Edurne Lázaro; Federico Román; Emilia Cercenado; César García-Rey; María Pérez-Vázquez; Jesús Oteo; Francisco de Abajo
Journal:  Antimicrob Agents Chemother       Date:  2007-04-30       Impact factor: 5.191

6.  Correlation between hydrolysis of the -lactam bond of the cephalosporin nucleus and expulsion of the 3-substituent.

Authors:  C H O'Callaghan; S M Kirby; A Morris; R E Waller; R E Duncombe
Journal:  J Bacteriol       Date:  1972-06       Impact factor: 3.490

7.  Diversity of beta-lactam resistance-conferring amino acid substitutions in penicillin-binding protein 3 of Haemophilus influenzae.

Authors:  Henri Dabernat; Catherine Delmas; Martine Seguy; Roseline Pelissier; Genevieve Faucon; Safia Bennamani; Christophe Pasquier
Journal:  Antimicrob Agents Chemother       Date:  2002-07       Impact factor: 5.191
  7 in total
  11 in total

1.  Epidemiology and evolution of antibiotic resistance of Haemophilus influenzae in children 5 years of age or less in France, 2001-2008: a retrospective database analysis.

Authors:  H Dabernat; C Delmas
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2012-04-27       Impact factor: 3.267

2.  Characteristics of Haemophilus influenzae invasive isolates from Portugal following routine childhood vaccination against H. influenzae serotype b (2002-2010).

Authors:  M P Bajanca-Lavado; A S Simões; C R Betencourt; R Sá-Leão
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2013-10-24       Impact factor: 3.267

3.  Efficacy of simulated cefditoren versus amoxicillin-clavulanate free concentrations in countering intrastrain ftsI gene diffusion in Haemophilus influenzae.

Authors:  Natalia González; Lorenzo Aguilar; David Sevillano; Maria-Jose Giménez; Luis Alou; Fabio Cafini; Martha Torrico; Ana-Maria López; Pilar Coronel; Jose Prieto
Journal:  Antimicrob Agents Chemother       Date:  2011-04-04       Impact factor: 5.191

4.  Polymorphism in ftsI gene and {beta}-lactam susceptibility in Portuguese Haemophilus influenzae strains: clonal dissemination of beta-lactamase-positive isolates with decreased susceptibility to amoxicillin/clavulanic acid.

Authors:  Ana Raquel Barbosa; Maria Giufrè; Marina Cerquetti; Maria Paula Bajanca-Lavado
Journal:  J Antimicrob Chemother       Date:  2011-01-25       Impact factor: 5.790

5.  Update on the clinical utility and optimal use of cefditoren.

Authors:  José Barberán; Lorenzo Aguilar; María-José Giménez
Journal:  Int J Gen Med       Date:  2012-05-21

Review 6.  Cefditoren in upper and lower community-acquired respiratory tract infections.

Authors:  Francisco Soriano; María-José Giménez; Lorenzo Aguilar
Journal:  Drug Des Devel Ther       Date:  2011-02-09       Impact factor: 4.162

7.  Drug resistance in community-acquired respiratory tract infections: role for an emerging antibacterial.

Authors:  Lorenzo Aguilar; María-José Giménez; José Barberán
Journal:  Infect Drug Resist       Date:  2010-06-18       Impact factor: 4.003

Review 8.  Revisiting cefditoren for the treatment of community-acquired infections caused by human-adapted respiratory pathogens in adults.

Authors:  María-José Giménez; Lorenzo Aguilar; Juan José Granizo
Journal:  Multidiscip Respir Med       Date:  2018-11-02

9.  Nationwide survey of the development of drug resistance in the pediatric field in 2007 and 2010: drug sensitivity of Haemophilus influenzae in Japan (second report).

Authors:  Tadashi Hoshino; Yoshitake Sato; Yoshikiyo Toyonaga; Hideaki Hanaki; Keisuke Sunakawa
Journal:  J Infect Chemother       Date:  2013-04-07       Impact factor: 2.211

10.  Multilocus sequence typing and ftsI sequencing: a powerful tool for surveillance of penicillin-binding protein 3-mediated beta-lactam resistance in nontypeable Haemophilus influenzae.

Authors:  Dagfinn Skaare; Inger Lill Anthonisen; Dominique A Caugant; Andrew Jenkins; Martin Steinbakk; Linda Strand; Arnfinn Sundsfjord; Yngvar Tveten; Bjørn-Erik Kristiansen
Journal:  BMC Microbiol       Date:  2014-05-20       Impact factor: 3.605
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