Literature DB >> 1895311

Nitroheterocycle reduction as a paradigm for intramolecular catalysis of drug delivery to hypoxic cells.

A Firestone1, R T Mulcahy, R F Borch.   

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Year:  1991        PMID： 1895311     DOI： 10.1021/jm00113a040

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  4 in total

Review 1.  Recent developments in the design of bioreductive drugs.

Authors:  W A Denny; W R Wilson; M P Hay
Journal:  Br J Cancer Suppl       Date:  1996-07

2.  Cyclophosphamides as hypoxia-activated diffusible cytotoxins: a theoretical study.

Authors:  J H Wu; C A Reynolds
Journal:  J Comput Aided Mol Des       Date:  2000-05       Impact factor: 3.686

3.  Design, synthesis and biological evaluations of a long-acting, hypoxia-activated prodrug of fasudil, a ROCK inhibitor, to reduce its systemic side-effects.

Authors:  Taslim A Al-Hilal; Mohammad Anwar Hossain; Ahmed Alobaida; Farzana Alam; Ali Keshavarz; Eva Nozik-Grayck; Kurt R Stenmark; Nadezhda A German; Fakhrul Ahsan
Journal:  J Control Release       Date:  2021-04-26       Impact factor: 11.467

4.  Reductive Activity and Mechanism of Hypoxia- Targeted AGT Inhibitors: An Experimental and Theoretical Investigation.

Authors:  Weinan Xiao; Guohui Sun; Tengjiao Fan; Junjun Liu; Na Zhang; Lijiao Zhao; Rugang Zhong
Journal:  Int J Mol Sci       Date:  2019-12-13       Impact factor: 5.923
  4 in total

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