| Literature DB >> 18952002 |
Félix M Goñi1, Alicia Alonso, Luis A Bagatolli, Rhoderick E Brown, Derek Marsh, Manuel Prieto, Jenifer L Thewalt.
Abstract
The present paper reviews the phase properties of phosphatidylcholine-sphingomyelin-cholesterol mixtures, that are often used as models for membrane "raft" microdomains. The available data based on X-ray, microscopic and spectroscopic observations, surface pressure and calorimetric measurements, and detergent solubilization assays, are critically evaluated and rationalized in terms of triangular phase diagrams. The remaining uncertainties are discussed specifically and separately from the data on which a consensus appears to exist.Entities:
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Year: 2008 PMID： 18952002 PMCID： PMC2600854 DOI： 10.1016/j.bbalip.2008.09.002
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002