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Literature DB >> 18948997

Ageing, oxidative stress and cancer: paradigms in parallax.

Abstract

Two paradigms central to geroscience research are that aging is associated with increased oxidative stress and increased cancer risk. Therefore, it could be deduced that cancers arising with ageing will show evidence of increased oxidative stress. Recent studies of gene expression in age-controlled breast cancer cases indicate that this deduction is false, posing parallax views of these two paradigms, and highlighting the unanswered question: does ageing cause or simply permit cancer development?

Entities: CellLine Chemical Disease Gene Species

Mesh：

Year: 2008 PMID： 18948997 PMCID： PMC2603471 DOI： 10.1038/nrc2522

Source DB: PubMed Journal: Nat Rev Cancer ISSN： 1474-175X Impact factor: 60.716

57 in total

Review 1. Epidermal growth factor receptor/HER2/insulin-like growth factor receptor signalling and oestrogen receptor activity in clinical breast cancer.

Authors: J M Gee; J F Robertson; E Gutteridge; I O Ellis; S E Pinder; M Rubini; R I Nicholson
Journal: Endocr Relat Cancer Date: 2005-07 Impact factor: 5.678

Review 2. Free radicals, metals and antioxidants in oxidative stress-induced cancer.

Authors: M Valko; C J Rhodes; J Moncol; M Izakovic; M Mazur
Journal: Chem Biol Interact Date: 2006-01-23 Impact factor: 5.192

3. AKT activation predicts outcome in breast cancer patients treated with tamoxifen.

Authors: Tove Kirkegaard; Caroline J Witton; Liane M McGlynn; Sian M Tovey; Barbara Dunne; Alison Lyon; John M S Bartlett
Journal: J Pathol Date: 2005-10 Impact factor: 7.996

4. Estrogen-regulated genes predict survival in hormone receptor-positive breast cancers.

Authors: Daniel S Oh; Melissa A Troester; Jerry Usary; Zhiyuan Hu; Xiaping He; Cheng Fan; Junyuan Wu; Lisa A Carey; Charles M Perou
Journal: J Clin Oncol Date: 2006-02-27 Impact factor: 44.544

Review 5. Mitochondria, oxygen free radicals, disease and ageing.

Authors: S Raha; B H Robinson
Journal: Trends Biochem Sci Date: 2000-10 Impact factor: 13.807

6. Upregulation of PKC-delta contributes to antiestrogen resistance in mammary tumor cells.

Authors: Sanaa M Nabha; Selina Glaros; Meng Hong; Anne E Lykkesfeldt; Rachel Schiff; Kent Osborne; Kaladhar B Reddy
Journal: Oncogene Date: 2005-04-28 Impact factor: 9.867

Review 7. Cancer and ageing: a nexus at several levels.

Authors: Lodovico Balducci; William B Ershler
Journal: Nat Rev Cancer Date: 2005-08 Impact factor: 60.716

8. Activation of mitogen-activated protein kinase in estrogen receptor alpha-positive breast cancer cells in vitro induces an in vivo molecular phenotype of estrogen receptor alpha-negative human breast tumors.

Authors: Chad J Creighton; Amy M Hilger; Shalini Murthy; James M Rae; Arul M Chinnaiyan; Dorraya El-Ashry
Journal: Cancer Res Date: 2006-04-01 Impact factor: 12.701

9. Genes regulated by estrogen in breast tumor cells in vitro are similarly regulated in vivo in tumor xenografts and human breast tumors.

Authors: Chad J Creighton; Kevin E Cordero; Jose M Larios; Rebecca S Miller; Michael D Johnson; Arul M Chinnaiyan; Marc E Lippman; James M Rae
Journal: Genome Biol Date: 2006-04-07 Impact factor: 13.583

10. Genes responsive to both oxidant stress and loss of estrogen receptor function identify a poor prognosis group of estrogen receptor positive primary breast cancers.

Authors: Christina Yau; Christopher C Benz
Journal: Breast Cancer Res Date: 2008-07-17 Impact factor: 6.466

85 in total

1. F2-isoprostanes and Metabolite, and Breast Cancer Risk.

Authors: Qi Dai; Xiangzhu Zhu
Journal: N Am J Med Sci (Boston) Date: 2009-07

2. Shortened telomeres in individuals with abuse in alcohol consumption.

Authors: Sofia Pavanello; Mirjam Hoxha; Laura Dioni; Pier Alberto Bertazzi; Rossella Snenghi; Alessandro Nalesso; Santo Davide Ferrara; Massimo Montisci; Andrea Baccarelli
Journal: Int J Cancer Date: 2011-04-25 Impact factor: 7.396

3. tert-butyl hydroperoxide, an organic peroxide, causes temporary delay in hair growth in a neonatal rat model.

Authors: T C Wikramanayake; J Simon; L M Mauro; C I Perez; B Roberts; G Elgart; E Alvarez-Connelly; L A Schachner; J J Jimenez
Journal: Clin Exp Dermatol Date: 2011-03-21 Impact factor: 3.470

Review 4. Forkhead box M1 transcription factor: a novel target for cancer therapy.

Authors: Zhiwei Wang; Aamir Ahmad; Yiwei Li; Sanjeev Banerjee; Dejuan Kong; Fazlul H Sarkar
Journal: Cancer Treat Rev Date: 2009-12-22 Impact factor: 12.111

Review 5. Breast cancer phenotypes regulated by tissue factor-factor VII pathway: Possible therapeutic targets.

Authors: Shiro Koizume; Yohei Miyagi
Journal: World J Clin Oncol Date: 2014-12-10

Review 6. Metabolic regulation of oxygen and redox homeostasis by p53: lessons from evolutionary biology?

Authors: Jie Zhuang; Wenzhe Ma; Cory U Lago; Paul M Hwang
Journal: Free Radic Biol Med Date: 2012-07-25 Impact factor: 7.376

7. Genetic and cellular characterization of Caenorhabditis elegans mutants abnormal in the regulation of many phase II enzymes.

Authors: Koichi Hasegawa; Johji Miwa
Journal: PLoS One Date: 2010-06-17 Impact factor: 3.240

Review 8. Biology-driven cancer drug development: back to the future.

Authors: Christopher J Lord; Alan Ashworth
Journal: BMC Biol Date: 2010-04-12 Impact factor: 7.431

9. Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor.

Authors: Koichi Hasegawa; Satsuki Miwa; Kaname Tsutsumiuchi; Johji Miwa
Journal: PLoS One Date: 2010-02-17 Impact factor: 3.240

10. Immunohistochemical analysis of oxidative stress and DNA repair proteins in normal mammary and breast cancer tissues.

Authors: Carol D Curtis; Daniel L Thorngren; Ann M Nardulli
Journal: BMC Cancer Date: 2010-01-11 Impact factor: 4.430