Literature DB >> 18947173

Diagnosis and treatment of pulmonary arterial hypertension and atrial fibrillation in an adult chimpanzee (Pan troglodytes).

Michael L Lammey1, Cynthia J Doane, Andrew Gigliotti, D Rick Lee, Meg M Sleeper.   

Abstract

This report describes the diagnosis and treatment of pulmonary arterial hypertension (PAH) in an adult male captive chimpanzee. Although cardiovascular disease in general is common in human and great apes, diagnosis and treatment of PAH in nonhuman primates are uncommon. In the case we present, the adult chimpanzee was diagnosed with an arrhythmia during an annual physical examination and later with PAH during a scheduled cardiovascular evaluation. PAH can either be primary or secondary and can lead to right ventricular overload and heart failure. This description is the first case study of pulmonary arterial hypertension in a great ape species.

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Year:  2008        PMID: 18947173      PMCID: PMC2691534     

Source DB:  PubMed          Journal:  J Am Assoc Lab Anim Sci        ISSN: 1559-6109            Impact factor:   1.232


  11 in total

Review 1.  Treatment of pulmonary arterial hypertension.

Authors:  Marc Humbert; Olivier Sitbon; Gérald Simonneau
Journal:  N Engl J Med       Date:  2004-09-30       Impact factor: 91.245

2.  Evidence for vascular remodeling in the lungs of macaques infected with simian immunodeficiency virus/HIV NEF recombinant virus.

Authors:  John Marecki; Carlyne Cool; Norbert Voelkel; Paul Luciw; Sonia Flores
Journal:  Chest       Date:  2005-12       Impact factor: 9.410

3.  Sildenafil improves exercise hemodynamics and oxygen uptake in patients with systolic heart failure.

Authors:  Gregory D Lewis; Justine Lachmann; Janice Camuso; John J Lepore; Jordan Shin; Maryann E Martinovic; David M Systrom; Kenneth D Bloch; Marc J Semigran
Journal:  Circulation       Date:  2006-12-18       Impact factor: 29.690

4.  Sildenafil citrate therapy for pulmonary arterial hypertension.

Authors:  Nazzareno Galiè; Hossein A Ghofrani; Adam Torbicki; Robyn J Barst; Lewis J Rubin; David Badesch; Thomas Fleming; Tamiza Parpia; Gary Burgess; Angelo Branzi; Friedrich Grimminger; Marcin Kurzyna; Gérald Simonneau
Journal:  N Engl J Med       Date:  2005-11-17       Impact factor: 91.245

5.  Electrocardiogram abnormalities in captive chimpanzees (Pan troglodytes).

Authors:  Cynthia J Doane; D Rick Lee; Meg M Sleeper
Journal:  Comp Med       Date:  2006-12       Impact factor: 0.982

6.  Endocardial fibrosis associated with monocrotaline-induced pulmonary hypertension in nonhuman primates (Macaca arctoides).

Authors:  C F Chesney; J R Allen
Journal:  Am J Vet Res       Date:  1973-12       Impact factor: 1.156

Review 7.  Systemic pathology of chimpanzees.

Authors:  R E Schmidt
Journal:  J Med Primatol       Date:  1975       Impact factor: 0.667

8.  Successful treatment of idiopathic dilated cardiomyopathy in an adult chimpanzee (Pan troglodytes).

Authors:  Meg M Sleeper; Cynthia J Doane; Paul H Langner; Stephen Curtis; Kelly Avila; D Rick Lee
Journal:  Comp Med       Date:  2005-02       Impact factor: 0.982

9.  Hemodynamic and echocardiographic evaluation of the stumptailed macaque: a potential nonhuman primate model for pulmonary vascular disease.

Authors:  K M Weesner; K Kaplan
Journal:  J Med Primatol       Date:  1987       Impact factor: 0.667

10.  Prevention of endotoxin-induced pulmonary hypertension in primates by the use of a selective thromboxane synthetase inhibitor, OKY 1581.

Authors:  L C Casey; J R Fletcher; M I Zmudka; P W Ramwell
Journal:  J Pharmacol Exp Ther       Date:  1982-08       Impact factor: 4.030

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  5 in total

1.  Use of an implantable loop recorder in the investigation of arrhythmias in adult captive chimpanzees (Pan troglodytes).

Authors:  Michael L Lammey; Raven Jackson; John J Ely; D Rick Lee; Meg M Sleeper
Journal:  Comp Med       Date:  2011-02       Impact factor: 0.982

2.  Chronic diseases in captive geriatric female Chimpanzees (Pan troglodytes).

Authors:  Elizabeth A Nunamaker; D Rick Lee; Michael L Lammey
Journal:  Comp Med       Date:  2012-04       Impact factor: 0.982

Review 3.  Natural pathology of the captive chimpanzee (Pan troglodytes): A 35-year review.

Authors:  Shyamesh Kumar; Hannah Laurence; Michael A Owston; R Mark Sharp; Priscilla Williams; Robert E Lanford; Gene B Hubbard; Edward J Dick
Journal:  J Med Primatol       Date:  2017-05-23       Impact factor: 0.667

Review 4.  Natural mortality and cause of death analysis of the captive chimpanzee (Pan troglodytes): A 35-year review.

Authors:  Hannah Laurence; Shyamesh Kumar; Michael A Owston; Robert E Lanford; Gene B Hubbard; Edward J Dick
Journal:  J Med Primatol       Date:  2017-04-18       Impact factor: 0.667

5.  The influence of body mass index, age and sex on inflammatory disease risk in semi-captive Chimpanzees.

Authors:  Vincent Obanda; George Paul Omondi; Patrick Ilukol Chiyo
Journal:  PLoS One       Date:  2014-08-14       Impact factor: 3.240

  5 in total

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