Literature DB >> 18946981

A literature review of different pressure ulcer models from 1942-2005 and the development of an ideal animal model.

P K T Nguyen1, A L Smith, K J Reynolds.   

Abstract

The literature from 1942-2005 was reviewed in order to determine an inexpensive animal model which can closely mimic pressure ulcers seen in humans of varying ages, without the need for surgical procedures. Two animal models for producing pressure ulcers were found to be inexpensive: pigs to mimic pressure ulcers in young humans due to their fixed skin, and rats to mimic pressure ulcers in the elderly due to their loose skin. The methods which were found to be inexpensive, reproducible, non-invasive and easy to carry out without the need of a surgeon or specialist were the use of magnets for rat models and the use of a cast placed over a bony prominence for pig models.

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Year:  2008        PMID: 18946981     DOI: 10.1007/bf03179348

Source DB:  PubMed          Journal:  Australas Phys Eng Sci Med        ISSN: 0158-9938            Impact factor:   1.430


  6 in total

1.  Adipose stromal cells repair pressure ulcers in both young and elderly mice: potential role of adipogenesis in skin repair.

Authors:  Amy L Strong; Annie C Bowles; Connor P MacCrimmon; Trivia P Frazier; Stephen J Lee; Xiying Wu; Adam J Katz; Barbara Gawronska-Kozak; Bruce A Bunnell; Jeffrey M Gimble
Journal:  Stem Cells Transl Med       Date:  2015-04-21       Impact factor: 6.940

2.  A non-invasive method to produce pressure ulcers of varying severity in a spinal cord-injured rat model.

Authors:  A K Ahmed; C R Goodwin; R Sarabia-Estrada; F Lay; A M Ansari; C Steenbergen; C Pang; R Cohen; L J Born; A E Matsangos; C Ng; G P Marti; N Abu-Bonsrah; N A Phillips; I Suk; D M Sciubba; J W Harmon
Journal:  Spinal Cord       Date:  2016-06-21       Impact factor: 2.772

3.  Pathologic changes of wound tissue in rats with stage III pressure ulcers treated by transplantation of human amniotic epithelial cells.

Authors:  Xilan Zheng; Zhixia Jiang; Aiting Zhou; Limei Yu; Mingtao Quan; Huagang Cheng
Journal:  Int J Clin Exp Pathol       Date:  2015-10-01

4.  Three-Dimensional-Printed External Scaffolds Mitigate Loss of Volume and Topography in Engineered Elastic Cartilage Constructs.

Authors:  Xue Dong; Ishani D Premaratne; Jaime L Bernstein; Arash Samadi; Alexandra J Lin; Yoshiko Toyoda; Jongkil Kim; Lawrence J Bonassar; Jason A Spector
Journal:  Cartilage       Date:  2021-10-12       Impact factor: 3.117

5.  Deep tissue injury rat model for pressure ulcer research on spinal cord injury.

Authors:  Fang Lin; Atek Pandya; Andrew Cichowski; Mauli Modi; Briana Reprogle; Dongkeun Lee; Norio Kadono; Mohsen Makhsous
Journal:  J Tissue Viability       Date:  2009-12-16       Impact factor: 2.932

6.  Pressure ulcer healing promoted by adequate protein intake in rats.

Authors:  Zhanfen Qin; Yao Wang; Wei Zhao; Yanan Zhang; Yiqing Tian; Sujuan Sun; Xian Li
Journal:  Exp Ther Med       Date:  2018-03-08       Impact factor: 2.447

  6 in total

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