Literature DB >> 18945653

Quality of life of patients and medical cost of "half elemental diet" as maintenance therapy for Crohn's disease: secondary outcomes of a randomised controlled trial.

S Takagi1, K Utsunomiya, S Kuriyama, H Yokoyama, S Takahashi, K Umemura, M Iwabuchi, H Takahashi, S Takahashi, Y Kinouchi, N Hiwatashi, Y Funayama, I Sasaki, I Tsuji, T Shimosegawa.   

Abstract

BACKGROUND/AIM: Quality of life (QOL) of the patients and medical costs are important in current medical treatments, especially those for chronic diseases. We have reported the effectiveness of 'half elemental diet (ED)' as maintenance therapy for patients with Crohn's disease (CD). The aim of this study was to evaluate the QOL of CD patients and medical costs of half-ED.
METHODS: Fifty-one CD patients in remission were randomly assigned to a half-ED group (n=26) or a free diet group (n=25). The primary outcome measure was the occurrence of relapse during a 2-year period. This time, we investigated the QOL of the patients and medical costs of half-ED, as secondary outcomes. QOL was evaluated using the Japanese version of the IBDQ scoring system, and medical costs were calculated monthly from the receipts.
RESULTS: IBDQ score was not significantly different between the two groups at 1 and 13 months after the start of maintenance treatment. Medical costs were not significantly different between them either. This study showed that half-ED therapy did not affect the treatment of CD patients, neither regarding their QOL nor medical costs.
CONCLUSION: This study has confirmed this half-ED therapy is beneficial for patients with Crohn's disease.

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Year:  2008        PMID: 18945653     DOI: 10.1016/j.dld.2008.09.007

Source DB:  PubMed          Journal:  Dig Liver Dis        ISSN: 1590-8658            Impact factor:   4.088


  10 in total

1.  Specialized enteral nutrition therapy in Crohn's disease patients on maintenance infliximab therapy: a meta-analysis.

Authors:  Douglas L Nguyen; Lena B Palmer; Emily T Nguyen; Stephen A McClave; Robert G Martindale; Matthew L Bechtold
Journal:  Therap Adv Gastroenterol       Date:  2015-07       Impact factor: 4.409

Review 2.  Crohn's disease.

Authors:  Sarah C Mills; Alexander C von Roon; Paris P Tekkis; Timothy R Orchard
Journal:  BMJ Clin Evid       Date:  2011-04-27

Review 3.  Advances in nutritional therapy in inflammatory bowel diseases: Review.

Authors:  Andrzej Wędrychowicz; Andrzej Zając; Przemysław Tomasik
Journal:  World J Gastroenterol       Date:  2016-01-21       Impact factor: 5.742

4.  Nutritional management of Crohn's disease.

Authors:  Clare F Donnellan; Lee H Yann; Simon Lal
Journal:  Therap Adv Gastroenterol       Date:  2013-05       Impact factor: 4.409

5.  Effect of amino acid-based formula added to four-food elimination in adult eosinophilic esophagitis patients: A randomized clinical trial.

Authors:  Willemijn E de Rooij; Berber Vlieg-Boerstra; Marijn J Warners; Marleen T J Van Ampting; Betty C A M van Esch; Simone R B M Eussen; Albert J Bredenoord
Journal:  Neurogastroenterol Motil       Date:  2021-11-18       Impact factor: 3.960

Review 6.  Enteral Nutrition in the Management of Pediatric and Adult Crohn's Disease.

Authors:  Tawnya Hansen; Donald R Duerksen
Journal:  Nutrients       Date:  2018-04-26       Impact factor: 5.717

7.  Systematic review: outcomes and adverse events from randomised trials in Crohn's disease.

Authors:  Heather Catt; Dyfrig Hughes; Jamie J Kirkham; Keith Bodger
Journal:  Aliment Pharmacol Ther       Date:  2019-03-03       Impact factor: 8.171

8.  Effectiveness of concomitant enteral nutrition therapy and infliximab for maintenance treatment of Crohn's disease in adults.

Authors:  Fumihito Hirai; Hiroshi Ishihara; Shinichirou Yada; Motohiro Esaki; Tomohisa Ohwan; Ryoichi Nozaki; Shinya Ashizuka; Haruhiko Inatsu; Hidehisa Ohi; Kunihiko Aoyagi; Yohei Mizuta; Takayuki Matsumoto; Toshiyuki Matsui
Journal:  Dig Dis Sci       Date:  2012-08-29       Impact factor: 3.199

Review 9.  An Examination of Diet for the Maintenance of Remission in Inflammatory Bowel Disease.

Authors:  Natasha Haskey; Deanna L Gibson
Journal:  Nutrients       Date:  2017-03-10       Impact factor: 5.717

Review 10.  Enteral Nutrition in Adult Crohn's Disease: Toward a Paradigm Shift.

Authors:  Simona Di Caro; Konstantinos C Fragkos; Katie Keetarut; Hui Fen Koo; Gregory Sebepos-Rogers; Hajeena Saravanapavan; John Barragry; Jennifer Rogers; Shameer J Mehta; Farooq Rahman
Journal:  Nutrients       Date:  2019-09-14       Impact factor: 5.717

  10 in total

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