Literature DB >> 18940143

Gastric pepsin in middle ear fluid of children with otitis media: clinical implications.

Zhaoping He1, Robert C O'Reilly, Devendra Mehta.   

Abstract

Gastroesophageal reflux and extraesophageal reflux have been postulated to be involved in the pathogenesis of otitis media. This is supported by recent studies revealing the presence of gastric pepsin in the middle ear space of children with otitis media but not in control patients without otitis media. Reflux's role in otitis media appears to be most pronounced in younger children and those with purulent effusions.

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Year:  2008        PMID: 18940143     DOI: 10.1007/s11882-008-0094-7

Source DB:  PubMed          Journal:  Curr Allergy Asthma Rep        ISSN: 1529-7322            Impact factor:   4.806


  42 in total

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Authors:  Andrea Tasker; Peter W Dettmar; Marguerite Panetti; James A Koufman; John P Birchall; Jeffery P Pearson
Journal:  Lancet       Date:  2002-02-09       Impact factor: 79.321

2.  Association of reflux with otitis media in children.

Authors:  Judith E C Lieu; P Ganesh Muthappan; Ravindra Uppaluri
Journal:  Otolaryngol Head Neck Surg       Date:  2005-09       Impact factor: 3.497

Review 3.  Systematic literature review of modifiable risk factors for recurrent acute otitis media in childhood.

Authors:  José Faibes Lubianca Neto; Lucas Hemb; Daniela Brunelli e Silva
Journal:  J Pediatr (Rio J)       Date:  2006 Mar-Apr       Impact factor: 2.197

4.  Otitis media-related antibiotic prescribing patterns, outcomes, and expenditures in a pediatric medicaid population.

Authors:  S Berman; P J Byrns; J Bondy; P J Smith; D Lezotte
Journal:  Pediatrics       Date:  1997-10       Impact factor: 7.124

5.  Interleukin-8 concentration predicts the neutrophil count in middle ear effusion.

Authors:  P S Nassif; S Q Simpson; A A Izzo; P J Nicklaus
Journal:  Laryngoscope       Date:  1997-09       Impact factor: 3.325

6.  Pharyngeal reflux in children with chronic otitis media with effusion.

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Journal:  Acta Otolaryngol       Date:  2004-12       Impact factor: 1.494

7.  Pepsin assay: a marker for reflux in pediatric glue ear.

Authors:  Ahmed M Abd El-Fattah; Gamal A Abdul Maksoud; Ahmed S Ramadan; Ahmed F Abdalla; Mohamed M Abdel Aziz
Journal:  Otolaryngol Head Neck Surg       Date:  2007-03       Impact factor: 3.497

Review 8.  Studies in otitis media: Children's Hospital of Pittsburgh-University of Pittsburgh progress report--2004.

Authors:  Charles D Bluestone
Journal:  Laryngoscope       Date:  2004-11       Impact factor: 3.325

9.  Human pepsin 3b peptide map sequence analysis, genotype and hydrophobic nature.

Authors:  A T Jones; J N Keen; N B Roberts
Journal:  J Chromatogr       Date:  1993-08-27

10.  Pediatric airway manifestations of gastroesophageal reflux.

Authors:  D M Burton; S M Pransky; R M Katz; D B Kearns; A B Seid
Journal:  Ann Otol Rhinol Laryngol       Date:  1992-09       Impact factor: 1.547

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  6 in total

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Review 2.  The association of premorbid diseases with chronic rhinosinusitis with and without polyps.

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3.  Comparison of Three Methods Used in the Diagnosis of Extraesophageal Reflux in Children with Chronic Otitis Media with Effusion.

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4.  Extra-Esophageal Pepsin from Stomach Refluxate Promoted Tonsil Hypertrophy.

Authors:  Jin Hyun Kim; Han-Sin Jeong; Kyung Mi Kim; Ye Jin Lee; Myeong Hee Jung; Jung Je Park; Jin Pyeong Kim; Seung Hoon Woo
Journal:  PLoS One       Date:  2016-04-08       Impact factor: 3.240

5.  Characterization of the nasopharyngeal and middle ear microbiota in gastroesophageal reflux-prone versus gastroesophageal reflux non-prone children.

Authors:  Stefan A Boers; Marjolein de Zeeuw; Ruud Jansen; Marc P van der Schroeff; Annemarie M C van Rossum; John P Hays; Suzanne J C Verhaegh
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2018-02-05       Impact factor: 3.267

6.  Correlation Between Tympanosclerosis and Helicobacter pylori.

Authors:  Nader Saki; Mojtaba Jahani; Alireza Samarbaf; Gholam Abbas Kaydani; Soheila Nikakhlagh; Malek Kenani; Sasan Mogehi
Journal:  Jundishapur J Microbiol       Date:  2015-10-12       Impact factor: 0.747

  6 in total

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