Literature DB >> 18940137

Allergen tolerance versus the allergic march: the hygiene hypothesis revisited.

Kevin Tse1, Anthony A Horner.   

Abstract

In addition to genetics, several environmental variables appear to impact allergic risk. Meta-analyses of epidemiologic studies presented in this article demonstrate a correlation between specific ambient exposures (eg, livestock, pets, endotoxin, and unpasteurized milk ingestion) and reduced allergic risk during childhood. Additional laboratory investigations discussed in this review characterized the intrinsic immunostimulatory activities of living environments. Considered together, results of these investigations suggest a novel paradigm by which early-life home exposures to microbial products and other allergen-nonspecific immunostimulants modify allergic risk.

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Year:  2008        PMID： 18940137      PMCID： PMC2869282          DOI： 10.1007/s11882-008-0088-5

Source DB:  PubMed          Journal:  Curr Allergy Asthma Rep        ISSN： 1529-7322            Impact factor:   4.806


  72 in total

1.  House dust endotoxin and allergic sensitization in children.

Authors:  Ulrike Gehring; Wolfgang Bischof; Bärbel Fahlbusch; Heinz-Erich Wichmann; Joachim Heinrich
Journal:  Am J Respir Crit Care Med       Date:  2002-10-01       Impact factor: 21.405

2.  IRAK-M is a negative regulator of Toll-like receptor signaling.

Authors:  Koichi Kobayashi; Lorraine D Hernandez; Jorge E Galán; Charles A Janeway; Ruslan Medzhitov; Richard A Flavell
Journal:  Cell       Date:  2002-07-26       Impact factor: 41.582

3.  House dust extracts elicit Toll-like receptor-dependent dendritic cell responses.

Authors:  Jared Boasen; Dugald Chisholm; Lev Lebet; Shizuo Akira; Anthony A Horner
Journal:  J Allergy Clin Immunol       Date:  2005-07       Impact factor: 10.793

4.  The prevalence of and risk factors for atopy in early childhood: a whole population birth cohort study.

Authors:  S M Tariq; S M Matthews; E A Hakim; M Stevens; S H Arshad; D W Hide
Journal:  J Allergy Clin Immunol       Date:  1998-05       Impact factor: 10.793

5.  Exposure to farming in early life and development of asthma and allergy: a cross-sectional survey.

Authors:  J Riedler; C Braun-Fahrländer; W Eder; M Schreuer; M Waser; S Maisch; D Carr; R Schierl; D Nowak; E von Mutius
Journal:  Lancet       Date:  2001-10-06       Impact factor: 79.321

6.  Influence of dog ownership and high endotoxin on wheezing and atopy during infancy.

Authors:  Paloma Campo; Harpinder K Kalra; Linda Levin; Tiina Reponen; Rolanda Olds; Zana L Lummus; Seung-Hyun Cho; Gurjit K Khurana Hershey; James Lockey; Manuel Villareal; Sherry Stanforth; Grace Lemasters; David I Bernstein
Journal:  J Allergy Clin Immunol       Date:  2006-09-26       Impact factor: 10.793

Review 7.  Molecular mechanisms of endotoxin tolerance.

Authors:  Hongkuan Fan; James A Cook
Journal:  J Endotoxin Res       Date:  2004

8.  The effect of genetic and environmental factors on the prevalence of allergic disorders at the age of two years.

Authors:  S H Arshad; M Stevens; D W Hide
Journal:  Clin Exp Allergy       Date:  1993-06       Impact factor: 5.018

9.  Microbial exposure of rural school children, as assessed by levels of N-acetyl-muramic acid in mattress dust, and its association with respiratory health.

Authors:  Robert Theodoor van Strien; Regina Engel; Otto Holst; Albrecht Bufe; Waltraud Eder; Marco Waser; Charlotte Braun-Fahrländer; Josef Riedler; Dennis Nowak; Erika von Mutius
Journal:  J Allergy Clin Immunol       Date:  2004-05       Impact factor: 10.793

10.  Early endotoxin exposure and atopy development in infants: results of a birth cohort study.

Authors:  G Bolte; W Bischof; M Borte; I Lehmann; H-E Wichmann; J Heinrich
Journal:  Clin Exp Allergy       Date:  2003-06       Impact factor: 5.018
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  6 in total

Review 1.  Developments in the field of allergy in 2009 through the eyes of Clinical and Experimental Allergy.

Authors:  H W Chu; C M Lloyd; W Karmaus; P Maestrelli; P Mason; G Salcedo; J Thaikoottathil; A J Wardlaw
Journal:  Clin Exp Allergy       Date:  2010-11       Impact factor: 5.018

Review 2.  The role of costimulatory molecules in allergic disease and asthma.

Authors:  Vincent Lombardi; Abinav K Singh; Omid Akbari
Journal:  Int Arch Allergy Immunol       Date:  2009-09-29       Impact factor: 2.749

3.  Got milk? Understanding the farm milk effect in allergy and asthma prevention.

Authors:  Joyce E Yu; Rachel L Miller
Journal:  J Allergy Clin Immunol       Date:  2016-04-12       Impact factor: 10.793

Review 4.  Clinical immunology.

Authors:  J David M Edgar
Journal:  Ulster Med J       Date:  2011-01

Review 5.  Immunoglobulin G; structure and functional implications of different subclass modifications in initiation and resolution of allergy.

Authors:  Timothy H Scott-Taylor; Stefan-Claudiu Axinia; Sumeya Amin; Ruth Pettengell
Journal:  Immun Inflamm Dis       Date:  2017-11-21

Review 6.  Research Progress in Atopic March.

Authors:  Lan Yang; Jinrong Fu; Yufeng Zhou
Journal:  Front Immunol       Date:  2020-08-27       Impact factor: 7.561
  6 in total

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