| Literature DB >> 1894000 |
T Nakamura1, A Suyama, A Wada.
Abstract
The relation between codon usage and gene-expression levels is an intensively investigated and discussed topic in the field of molecular evolution. We statistically analyzed 25 Escherichia coli gene sequences by a new classification of synonymous codons and found that (i) there are two distinct types of linkage between codon usage and gene-expression levels in E. coli, and (ii) one of the two kinds of codon preferences (the codon preference concerned with interaction of GC/AT choice at three codon positions) is observed significantly in weakly expressed genes.Entities:
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Year: 1991 PMID: 1894000 DOI: 10.1016/0014-5793(91)80923-q
Source DB: PubMed Journal: FEBS Lett ISSN: 0014-5793 Impact factor: 4.124